Malaria elimination has recently been reinstated as a global health priority but current
therapies seem to be insufficient for the task. Elimination efforts require new drug classes …

This digest covers some of the most relevant progress in malaria drug discovery published
between 2010 and 2012. There is an urgent need to develop new antimalarial drugs. Such …

Drinking water contamination with heavy metals, particularly lead, is a persistent problem
worldwide with grave public health consequences. Existing purification methods often …

Malaria, a devastating infectious disease caused by Plasmodium spp., leads to roughly
655,000 deaths per year, mostly of African children. To compound the problem, drug …

Neglected tropical diseases (NTDs) refer to a group of infectious diseases, which though
treatable and/or preventable, remain a leading cause of morbidity and mortality among the …

Malaria is a disease that still affects a significant proportion of the global human population.
Whilst advances have been made in lowering the numbers of cases and deaths, it is clear …

The development of new antimalarial compounds remains a pivotal part of the strategy for
malaria elimination. Recent large-scale phenotypic screens have provided a wealth of …

Resistance is a constant challenge for anti-infective drug development. Since they kill
sensitive organisms, anti-infective agents are bound to exert an evolutionary pressure …

Background Despite recent successes at controlling malaria, progress has stalled with an
estimated 219 million cases and 435,000 deaths in 2017 alone. Combined with emerging …

Recent observations on the emergence of artemisinin resistant parasites have highlighted
the need for new antimalarial treatments. An HTS campaign led to the identification of the 1 …