Cells must adapt to changes in their environment to maintain cell, tissue and organismal
integrity in the face of mechanical, chemical or microbiological stress. Nuclear factor-κB (NF …

MicroRNAs (miRNAs) are endogenous 22 nt non-coding RNAs that target mRNAs for
cleavage or translational repression. Numerous miRNAs regulate programmed cell death …

Bone metastasis is an incurable complication of breast cancer. In advanced stages, patients
with estrogen-positive tumors experience a significantly higher incidence of bone metastasis …

To protect tissues and the organism from disease, potentially harmful cells are removed
through programmed cell death processes, including apoptosis and necroptosis. These …

Polyubiquitination of proteins has a pivotal role in the regulation of numerous cellular
functions such as protein degradation, DNA repair and cell signaling. As deregulation of …

The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …

Background Excessive and inappropriate immune responses are the hallmark of several
autoimmune disorders, including the inflammatory bowel diseases (IBD): Crohn's disease …

Hydrogen sulfide (H 2 S) is an air pollutant, having toxic effects on immune system.
Necroptosis has been discussed as a new form of cell death and plays an important role in …

Overexpression of the miR-17-92 cluster is a key oncogenic event in various cancer types.
The oncogenic effect of the miR-17-92 cluster is enhanced by cooperation between its …

Necroptosis has been discovered as a new paradigm of cell death and may play a key role
in heart disease and selenium (Se) deficiency. Hence, we detected the specific microRNA …