Periodontal complications of hyperglycemia/diabetes mellitus: epidemiologic complexity and clinical challenge

T Kocher, J König, WS Borgnakke, C Pink… - Periodontology …, 2018 - Wiley Online Library
This report provides a comprehensive overview of the adverse effects of hyperglycemia on
the periodontium. It combines data from literature reviews of original data from two large …

Systematic review and meta-analysis on the nonsurgical treatment of chronic periodontitis by means of scaling and root planing with or without adjuncts

CJ Smiley, SL Tracy, E Abt, BS Michalowicz… - The Journal of the …, 2015 - Elsevier
Background Conduct a systematic review and meta-analysis on nonsurgical treatment of
patients with chronic periodontitis by means of scaling and root planing (SRP) with or …

Analysis of matrix metalloproteinases, especially MMP‐8, in gingival crevicular fluid, mouthrinse and saliva for monitoring periodontal diseases

T Sorsa, UK Gursoy, S Nwhator… - Periodontology …, 2016 - Wiley Online Library
Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

The adjunctive use of host modulators in non‐surgical periodontal therapy. A systematic review of randomized, placebo‐controlled clinical studies

N Donos, E Calciolari, N Brusselaers… - Journal of clinical …, 2020 - Wiley Online Library
Background Considering the role of the inflammatory host response in the pathogenesis of
periodontitis, different host modulators have been proposed to enhance the outcomes of non …

Matrix metalloproteinases: contribution to pathogenesis, diagnosis and treatment of periodontal inflammation

T Sorsa, L Tjäderhane, YT Konttinen, A Lauhio… - Annals of …, 2006 - Taylor & Francis
Matrix metalloproteinases (MMPs) form a family of enzymes that mediate multiple functions
both in the tissue destruction and immune responses related to periodontal inflammation …

Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases

J Hu, PE Van den Steen, QXA Sang… - Nature reviews Drug …, 2007 - nature.com
Matrix metalloproteinases (MMPs) have outgrown the field of extracellular-matrix biology
and have progressed towards being important regulatory molecules in cancer and …

Matrix metalloproteinases (MMPs) in oral diseases

T Sorsa, L Tjäderhane, T Salo - Oral diseases, 2004 - Wiley Online Library
Matrix metalloproteinases (MMPs) are a group of enzymes that in concert are responsible for
the degradation of most extracellular matrix proteins during organogenesis, growth and …

Evidence-based clinical practice guideline on the nonsurgical treatment of chronic periodontitis by means of scaling and root planing with or without adjuncts

CJ Smiley, SL Tracy, E Abt, BS Michalowicz… - The Journal of the …, 2015 - Elsevier
Background A panel of experts convened by the American Dental Association Council on
Scientific Affairs presents an evidence-based clinical practice guideline on nonsurgical …

The role of matrix metalloproteinases in the oral environment

AR Hannas, JC Pereira, JM Granjeiro… - Acta Odontologica …, 2007 - Taylor & Francis
This review focuses specifically on matrix metalloproteinases (MMPs) and their role in
physiological and pathological extracellular matrix (ECM) remodeling and degradation …

Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm

D Herrera, B Alonso, R León… - Journal of clinical …, 2008 - Wiley Online Library
Objectives: The aim was to answer three relevant questions: can systemic antimicrobials be
efficacious if the biofilm is not disrupted? Can the type of debridement of the subgingival …