Polymeric in situ forming depots for long-acting drug delivery systems
Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …
for long-acting applications. Their effectiveness is attributed to essential characteristics such …
Recent advances in intranasal administration for brain-targeting delivery: a comprehensive review of lipid-based nanoparticles and stimuli-responsive gel formulations
J Koo, C Lim, KT Oh - International Journal of Nanomedicine, 2024 - Taylor & Francis
Addressing disorders related to the central nervous system (CNS) remains a complex
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …
A Nanoemulgel for Nose-to-Brain delivery of Quetiapine–QbD-Enabled formulation development & in-vitro characterization
Second-generation antipsychotics, quetiapine hemifumarate (QF), exhibited highly active
against negative and positive signs of psychosis. However, contemporary reports have …
against negative and positive signs of psychosis. However, contemporary reports have …
Fabrication of architectonic nanosponges for intraocular delivery of Brinzolamide: An insight into QbD driven optimization, in vitro characterization, and …
US Bagul, MV Nazirkar, AK Mane, SV Khot… - International Journal of …, 2024 - Elsevier
The intricate structure of the eye poses difficulties in drug targeting, which can be
surmounted with the help of nanoformulation strategies. With this view, brinzolamide …
surmounted with the help of nanoformulation strategies. With this view, brinzolamide …
Octa-Arginine-Conjugated Liposomal Nimodipine Incorporated in a Temperature-Responsive Gel for Nasoencephalic Delivery
S Hong, C Lin, J Hu, J Piao, MG Piao - Molecular Pharmaceutics, 2024 - ACS Publications
Nimodipine is the primary clinical drug used to treat cerebral vasospasm following
subarachnoid hemorrhage. Currently, tablets have low bioavailability when taken orally, and …
subarachnoid hemorrhage. Currently, tablets have low bioavailability when taken orally, and …
Mucoadhesive chitosan-poly (lactic-co-glycolic acid) nanoparticles for intranasal delivery of quetiapine–Development & characterization in physiologically relevant 3D …
Quetiapine hemifumarate (QF) delivery to the CNS via conventional formulations is
challenging due to poor solubility and lower oral bioavailability (9%). Similarly, many other …
challenging due to poor solubility and lower oral bioavailability (9%). Similarly, many other …
Hepatoprotective activity of Balsamodendron mukul extract against Paracetamol-induced liver toxicity in rats: In vivo pharmacological and toxicological evaluation
D Shah, N Mahurkar, D Gadhave, R Nikhate… - Annales …, 2023 - Elsevier
Overuse of the antipyretic agent Paracetamol (PCM) is linked to hepatotoxicity, which limits
its clinical use. The goal of this investigation was to find out how well Balsamodendron …
its clinical use. The goal of this investigation was to find out how well Balsamodendron …
[PDF][PDF] 替莫唑胺联合显微镜下经鼻蝶窦垂体瘤切除术治疗垂体瘤效果分析
崔博① - 中国医学创新, 2019 - zgyxcx.com
目的: 探讨替莫唑胺联合显微镜下经鼻蝶窦垂体瘤切除术治疗垂体瘤的效果. 方法: 选取2020 年4
月-2022 年4 月佳木斯市中心医院收治的102 例垂体瘤患者为对象, 随机分为对照组, 观察组 …
月-2022 年4 月佳木斯市中心医院收治的102 例垂体瘤患者为对象, 随机分为对照组, 观察组 …