Hematopoietic stem cell transplantation for sickle cell disease: Progress and challenges

ML Hulbert, S Shenoy - Pediatric blood & cancer, 2018 - Wiley Online Library
Sickle cell disease (SCD) presents challenges to hematopoietic stem cell transplantation
(HSCT), including donor availability and morbidity with age/disease severity. However …

Neuropathic pain in individuals with sickle cell disease

D Sharma, AM Brandow - Neuroscience Letters, 2020 - Elsevier
Pain is the most frequently occurring complication of sickle cell disease (SCD) and the
leading cause of hospitalizations for affected individuals. Acute pain episodes are also an …

Pathophysiology and principles of management of the many faces of the acute vaso‐occlusive crisis in patients with sickle cell disease

SK Ballas - European journal of haematology, 2015 - Wiley Online Library
Effective management of sickle cell pain entails a thorough understanding of its
pathophysiology and the pharmacogenomics of the opioids used to manage it. In recent …

Do we store packed red blood cells under “quasi-diabetic” conditions?

L Livshits, G Barshtein, D Arbell, A Gural, C Levin… - Biomolecules, 2021 - mdpi.com
Red blood cell (RBC) transfusion is one of the most common therapeutic procedures in
modern medicine. Although frequently lifesaving, it often has deleterious side effects. RBC …

Abnormal Neurologic Findings in Patients With Sickle Cell Disease Without a History of Major Neurologic Events

MB Nawaiseh, AM Yassin, MQ Al-Sabbagh… - Neurology: Clinical …, 2024 - AAN Enterprises
Background and Objectives Patients with sickle cell disease (SCD) are prone to
symptomatic neurologic complications. Previous studies reported accrual of neural injury …

Assessment of sleep-related disorders in children with sickle cell disease

JS Hankins, NI Verevkina, MP Smeltzer, S Wu… - …, 2014 - Taylor & Francis
Sleep-related disorders (SRDs) are common in sickle cell disease, however, identification
may be time-consuming. Simultaneous survey of multiple SRDs utilizing a simplified …

[PDF][PDF] Neuropathy, neuropathic pain, and sickle cell disease.

SK Ballas, DS Darbari - 2013 - jdc.jefferson.edu
In this issue of the journal Alvarez and colleagues [1] describe pain and other
nonneurological adverse events in children with sickle cell anemia (SS) and previous stroke …

Peripheral nerve pathology in sickle cell disease mice

KE Sadler, TR Lewis, TB Waltz, JC Besharse… - Pain …, 2019 - journals.lww.com
Objectives: In this brief report, we compared peripheral nerve morphology in tissues
obtained from Berkeley transgenic SCD mice and control animals. Methods: Sciatic nerves …

Muscle strength, power, and torque deficits in children with type SS sickle cell disease

KA Dougherty, C Bertolaso, JI Schall… - Journal of pediatric …, 2018 - journals.lww.com
Abstract In African-American children aged 5 to 17 years with and without type SS sickle cell
disease (SCD-SS), dominant hand maximal handgrip strength, peak power, and plantar …

Screening and Impact of Neuropathic Pain in Young Individuals With Sickle Cell Disease

A Adly, M Mohammed, A Aboata… - Pediatric Blood & …, 2024 - Wiley Online Library
Objective To assess the frequency of neuropathic pain (NP) and its impact in young patients
with sickle cell disease (SCD). Methods We used the ID‐Pain (ID‐P) questionnaire and a …