Objective To systematically review evidence on the efficacy and safety of sleep deprivation
(SD) as a treatment option for patients with unipolar or bipolar depression. Methods A …

Depression has been described as a process of behavioural withdrawal from overwhelming
aversive stressors, and which manifests itself in the diagnostic symptomatology for Major …

Depression represents an increasing global health epidemic with profound effects in the
workplace. Building a business case via the quantification of potentially avertable costs is …

Importance Depression and obesity are 2 prevalent disorders that have been repeatedly
shown to be associated. However, the mechanisms and temporal sequence underlying this …

The mechanisms and temporal sequence underlying the association between major
depressive disorder (MDD) and cardio-metabolic diseases are still poorly understood …

The re-emergence (ie 'breakthrough') of depressive symptoms despite maintenance
treatment of depression with antidepressant drugs is a complex clinical phenomenon …

This paper proposes a phenomenological approach to the diagnosis of depression, with the
aim of overcoming the broadness and nonspecificity of the concept of major depressive …

Objective The aims of the present study were to assess the associations between mood,
anxiety and substance use disorders, including their subtypes, and the prevalence of …

Although often considered as a mental disorder, depression is best described as a
behavioral-neurobiological phenomenon. In addition, although usually reported as a unitary …

The aims of this study were to investigate the associations of major depressive disorder
(MDD) and its subtypes (atypical, melancholic, combined, unspecified) with actigraphy …