Drug repurposing approach to fight COVID-19
Currently, there are no treatment options available for the deadly contagious disease,
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …
Hypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence
The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …
19) include cough, fever, and shortness of breath. However, other major events usually …
COVID-19, renin-angiotensin system and endothelial dysfunction
The newly emergent novel coronavirus disease 2019 (COVID-19) outbreak, which is caused
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
Influenza virus-related critical illness: pathophysiology and epidemiology
Influenza virus affects the respiratory tract by direct viral infection or by damage from the
immune system response. In humans, the respiratory epithelium is the only site where the …
immune system response. In humans, the respiratory epithelium is the only site where the …
Epidemiology and immune pathogenesis of viral sepsis
GL Lin, JP McGinley, SB Drysdale… - Frontiers in …, 2018 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …
Endothelial dysfunction in COVID-19: lessons learned from coronaviruses
E Gavriilaki, P Anyfanti, M Gavriilaki, A Lazaridis… - Current hypertension …, 2020 - Springer
Abstract Purpose of Review To review current literature on endothelial dysfunction with
previous coronaviruses, and present available data on the role of endothelial dysfunction in …
previous coronaviruses, and present available data on the role of endothelial dysfunction in …
The effect of short-term hyperglycemia on the innate immune system
Background Diabetes mellitus increases the susceptibility to infection by altering both the
innate and the adaptive immune systems. Hyperglycemia has been associated with adverse …
innate and the adaptive immune systems. Hyperglycemia has been associated with adverse …
Hiding in plain sight: an approach to treating patients with severe COVID-19 infection
DS Fedson, SM Opal, OM Rordam - MBio, 2020 - Am Soc Microbiol
Patients with COVID-19 infection are at risk of acute respiratory disease syndrome (ARDS)
and death. The tissue receptor for COVID-19 is ACE2, and higher levels of ACE2 can protect …
and death. The tissue receptor for COVID-19 is ACE2, and higher levels of ACE2 can protect …
Infection and risk of Parkinson's disease
RJ Smeyne, AJ Noyce, M Byrne… - Journal of …, 2021 - content.iospress.com
Parkinson's disease (PD) is thought to be caused by a combination of genetic and
environmental factors. Bacterial or viral infection has been proposed as a potential risk …
environmental factors. Bacterial or viral infection has been proposed as a potential risk …
[PDF][PDF] Lipid-lowering therapy and renin-angiotensin-aldosterone system inhibitors in the era of the COVID-19 pandemic
Lipid-lowering therapy and renin-angiotensin- aldosterone system inhibitors in the era of the
COVID-19 pandemic Page 1 Creative Commons licenses: This is an Open Access article …
COVID-19 pandemic Page 1 Creative Commons licenses: This is an Open Access article …