Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

P Grossen, D Witzigmann, S Sieber… - Journal of Controlled …, 2017 - Elsevier
The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

[HTML][HTML] Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers

S Mazumdar, D Chitkara, A Mittal - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Upconverting nanoparticles: assessing the toxicity

A Gnach, T Lipinski, A Bednarkiewicz… - Chemical Society …, 2015 - pubs.rsc.org
Lanthanide doped nanoparticles (Ln: NPs) hold promise as novel luminescent probes for
numerous applications in nanobiophotonics. Despite excellent photostability, narrowband …

Inhaled nanoparticles–An updated review

T Praphawatvet, JI Peters, RO Williams III - International journal of …, 2020 - Elsevier
We are providing an update to our previously published review paper on inhaled
nanoparticles, thus updating with the most recent reports in the literature. The field of …

Folate receptor-mediated delivery of mitoxantrone-loaded solid lipid nanoparticles to breast cancer cells

A Granja, C Nunes, CT Sousa, S Reis - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The standard breast cancer therapy still faces major challenges due to non-specific tumor
distribution and occurrence of dose-limiting adverse side-effects. Nanomedicine constitutes …

Surface modified multifunctional and stimuli responsive nanoparticles for drug targeting: current status and uses

PI Siafaka, N Üstündağ Okur, E Karavas… - International journal of …, 2016 - mdpi.com
Nanocarriers, due to their unique features, are of increased interest among researchers
working with pharmaceutical formulations. Polymeric nanoparticles and nanocapsules …

Engineered nanomaterials: The challenges and opportunities for nanomedicines

F Albalawi, MZ Hussein, S Fakurazi… - International journal of …, 2021 - Taylor & Francis
The emergence of nanotechnology as a key enabling technology over the past years has
opened avenues for new and innovative applications in nanomedicine. From the business …

Functional microgels: recent advances in their biomedical applications

G Agrawal, R Agrawal - Small, 2018 - Wiley Online Library
Here, a spotlight is shown on aqueous microgel particles which exhibit a great potential for
various biomedical applications such as drug delivery, cell imaging, and tissue engineering …

Understanding the effects of nanocapsular mechanical property on passive and active tumor targeting

Y Hui, D Wibowo, Y Liu, R Ran, HF Wang, A Seth… - ACS …, 2018 - ACS Publications
The physicochemical properties of nanoparticles (size, charge, and surface chemistry, etc.)
influence their biological functions often in complex and poorly understood ways. This …