Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies
and recombinant proteins, poses substantial challenges owing to their large size and …
and recombinant proteins, poses substantial challenges owing to their large size and …
Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications
The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …
applications, has certainly benefited from the application of synthetic polymers. However …
The chemistry of poly (2-oxazoline) s
B Verbraeken, BD Monnery, K Lava… - European Polymer …, 2017 - Elsevier
As we celebrate the 50th birthday of the discovery of poly (2-alkyl/aryl-2-oxazoline) s (PAOx)
this year we see a research field that is rapidly expanding after some lesser academic …
this year we see a research field that is rapidly expanding after some lesser academic …
Poly (2‐oxazoline) s: A comprehensive overview of polymer structures and their physical properties
M Glassner, M Vergaelen… - Polymer …, 2018 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) are of increasing importance for a wide range of
applications, mostly in the biomedical field. This review describes the synthesis of 2 …
applications, mostly in the biomedical field. This review describes the synthesis of 2 …
Poly (2‐oxazoline) s as Polymer Therapeutics
Abstract Poly (2‐oxazoline) s (POx) are currently discussed as an upcoming polymer
platform for biomaterials design and especially for polymer therapeutics. POx meet specific …
platform for biomaterials design and especially for polymer therapeutics. POx meet specific …
Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics
Synthetic methods in polymer chemistry have evolved tremendously during the last decade.
Nowadays more and more attention is devoted to the application of those tools in the …
Nowadays more and more attention is devoted to the application of those tools in the …
Poly (2‐Oxazoline) s–Are They More Advantageous for Biomedical Applications Than Other Polymers?
Abstract Poly (2‐alkyl‐2‐oxazoline) s are biocompatible polymers with polypeptide‐isomeric
structures that are attracting increasing interest as biomaterials for drug, gene, protein, and …
structures that are attracting increasing interest as biomaterials for drug, gene, protein, and …
Poly (2-oxazoline) s as materials for biomedical applications
VR de la Rosa - Journal of Materials Science: Materials in Medicine, 2014 - Springer
The conjunction of polymers and medicine enables the development of new materials that
display novel features, opening new ways to administrate drugs, design implants and …
display novel features, opening new ways to administrate drugs, design implants and …
Multifunctional nanoparticles for targeted delivery of immune activating and cancer therapeutic agents
Nanoparticles (NPs) have been extensively investigated for applications in both
experimental and clinical settings to improve delivery efficiency of therapeutic and …
experimental and clinical settings to improve delivery efficiency of therapeutic and …
Protein–polymer conjugation—moving beyond PEGylation
Y Qi, A Chilkoti - Current opinion in chemical biology, 2015 - Elsevier
Highlights•Limitations of conjugating poly (ethylene glycol) to proteins and peptides have
become increasingly apparent.•Various polymers have shown promise as PEG …
become increasingly apparent.•Various polymers have shown promise as PEG …