The most fundamental feature of cellular form is size, which sets the scale of all cell
biological processes. Growth, form, and function are all necessarily linked in cell biology, but …

Cells of a given type maintain a characteristic cell size to function efficiently in their
ecological or organismal context. They achieve this through the regulation of growth rates or …

Cell size fundamentally affects all biosynthetic processes by determining the scale of
organelles and influencing surface transport,. Although extensive studies have identified …

A classic problem in microbiology is that bacteria display two types of growth behavior when
cultured on a mixture of two carbon sources: the two sources are sequentially consumed …

To maintain a constant cell size, dividing cells have to coordinate cell-cycle events with cell
growth. This coordination has long been supposed to rely on the existence of size …

In the noisy cellular environment, gene products are subject to inherent random fluctuations
in copy numbers over time. How cells ensure precision in the timing of key intracellular …

Although it has long been clear that cells actively regulate their size, the molecular
mechanisms underlying this regulation have remained poorly understood. In budding yeast …

The human body is programmed with definite quantities, magnitudes, and proportions. At the
microscopic level, such definite sizes manifest in individual cells-different cell types are …

Commitment to cell division at the end of G1 phase, termed Start in the budding yeast
Saccharomyces cerevisiae, is strongly influenced by nutrient availability. To identify new …

To understand how commitment to cell division in late G1 phase (Start) is controlled by
growth and nutrients in budding yeast, we determined the absolute concentrations of the …