Lung diseases are the leading cause of mortality worldwide. The currently available
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …

The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …

Interleukin-11 (IL-11) is a profibrotic cytokine essential for the differentiation of fibroblasts
into collagen-secreting, actin alpha 2, smooth muscle–positive (ACTA2+) myofibroblasts …

Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs
(miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently …

In the last decade, biological drugs have rapidly proliferated and have now become an
important therapeutic modality. This is because of their high potency, high specificity and …

Background First vaccines for prevention of Coronavirus disease 2019 (COVID‐19) are
becoming available but there is a huge and unmet need for specific forms of treatment. In …

Chitosan, as a biodegradable and biocompatible polymer, is characterized by anti-microbial
and anti-cancer properties. It lately has received a widespread interest for use as the …

Therapeutic gene silencing promises significant progress in pharmacotherapy, including
considerable expansion of the druggable target space and the possibility for treating orphan …

Drugs are introduced into the body by numerous routes such as enteral (oral, sublingual and
rectum administration), parenteral (intravascular, intramuscular, subcutaneous and …

With the rapid development of biopharmaceuticals and the outbreak of COVID-19, the world
has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have …