The complex pathobiology of late-onset Alzheimer's disease (AD) poses significant
challenges to therapeutic and preventative interventions. Despite these difficulties …

Anxiety disorders are a group of prevalent and heritable neuropsychiatric diseases. We
previously conducted a genome-wide association study (GWAS) which identified genomic …

Since the first genome-wide association study (GWAS) identifying variants associated with
myocardial infarction was published over 20 years ago, GWASs have emerged as a …

Schizophrenia is a serious mental illness affecting 0.7% of the world's population. Despite
over 50 years of schizophrenia drug identification and development, there have been no …

Background Depression and anxiety are the most common mental health problems in young
people. Currently, clinicians are advised to wait before initiating treatment for young people …

There are fundamental differences in the diagnostic process and the pathogenesis/
pathophysiology of mental disorders compared to other clinical areas that pose a challenge …

Background Knowledge of the association between parental personality disorders and
mental disorders in children is limited. To examine the association between parental …

Background The term eGene has been applied to define a gene whose expression level is
affected by at least one independent expression quantitative trait locus (eQTL). It is both …

Recent advancements in psychiatric genetics have sparked a lively debate on the
opportunities and pitfalls of incorporating polygenic scores into clinical practice. Yet, several …

Obsessive-compulsive disorder (OCD) affects~ 1% of the population and exhibits a high
SNP-heritability, yet previous genome-wide association studies (GWAS) have provided …