Interleukin-33 (IL-33), a member of the IL-1 cytokine family and a multifunctional cytokine,
plays critical roles in maintaining host homeostasis and in pathological conditions, such as …

Progress in understanding nervous system-cancer interconnections has emphasized the
functional role of semaphorins (SEMAs) and their receptors, neuropilins (NRPs) and plexins …

Immune checkpoint inhibitors (ICIs) have caused revolutionary changes in cancer treatment,
but low response rates remain a challenge. Semaphorin 4A (Sema4A) modulates the …

Immunotherapy is revamping the therapeutic strategies for TNBC owing to its higher
mutational burden and tumour-associated antigens. One of the most intriguing …

A major part of important mammalian respiratory allergens belongs to the lipocalin family of
proteins. By this time, 19 respiratory mammalian lipocalin allergens have been registered in …

Interleukin 33 (IL-33), once predominantly recognized for its pro-tumoral activities, has
emerged as a multifunctional cytokine with antitumor properties. IL-33 pleiotropic activities …

Background and Objective: Treatment options for patients with advanced biliary tract cancer
(BTC) are limited. The programmed cell death protein-1 (PD-1) inhibitors may have …

Hallmark features of the tumor microenvironment include immune cells, stromal cells, blood
vessels, and extracellular matrix (ECM), providing a conducive environment for the growth …

Semaphorins are a large class of secreted or membrane-bound molecules. It has been
reported that semaphorins play important roles in regulating several hallmarks of cancer …

Background Lung cancer (LC) is the most prevalent cancer with a poor prognosis.
Semaphorin4A (Sema4A) is important in many physiological and pathological processes …