Potential effect of hydroxychloroquine in diabetes mellitus: a systematic review on preclinical and clinical trial studies

DZ Wondafrash, TZ Desalegn, EM Yimer… - Journal of diabetes …, 2020 - Wiley Online Library
Background. Diabetes mellitus is a chronic metabolic disorder characterized by persistent
hyperglycemia. It affects millions of people globally. In spite of many antidiabetic drugs that …

A critical review of the effects of hydroxychloroquine and chloroquine on the eye

N Costedoat-Chalumeau, B Dunogué, G Leroux… - Clinical reviews in …, 2015 - Springer
Hydroxychloroquine (HCQ) and chloroquine have been used for more than 50 years to treat
systemic lupus erythematosus (SLE) and other rheumatic diseases. In general, these drugs …

The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy

RB Melles, MF Marmor - JAMA ophthalmology, 2014 - jamanetwork.com
Importance Hydroxychloroquine sulfate is widely used for the long-term treatment of
autoimmune conditions but can cause irreversible toxic retinopathy. Prior estimations of risk …

[图书][B] Hydroxychloroquine and chloroquine retinopathy

DJ Browning - 2014 - Springer
Nomenclature is important, but confusing. Although the book focuses on chloroquine and
hydroxychloroquine, much of it applies to other related drugs (eg, quinacrine). These drugs …

Hydroxychloroquine-related retinal toxicity

HJ Ding, AK Denniston, VK Rao, C Gordon - Rheumatology, 2016 - academic.oup.com
HCQ is widely used for the treatment of rheumatic diseases, particularly lupus and RA. It is
generally well tolerated, but retinopathy is a concern. Retinopathy is rare, but is sight …

Hydroxychloroquine-induced retinal toxicity

IH Yusuf, P Charbel Issa, SJ Ahn - Frontiers in Pharmacology, 2023 - frontiersin.org
Long-term use of hydroxychloroquine can cause retinopathy, which may result in severe and
progressive visual loss. In the past decade, hydroxychloroquine use has markedly increased …

Disparity between visual fields and optical coherence tomography in hydroxychloroquine retinopathy

MF Marmor, RB Melles - Ophthalmology, 2014 - Elsevier
Purpose American Academy of Ophthalmology recommendations for screening for
hydroxychloroquine (HCQ) retinopathy advise objective measures, such as spectral-domain …

[HTML][HTML] Pericentral hydroxychloroquine retinopathy in Korean patients

DH Lee, RB Melles, SG Joe, JY Lee, JG Kim, CK Lee… - Ophthalmology, 2015 - Elsevier
Purpose A pericentral pattern of hydroxychloroquine (HCQ) retinopathy recently has been
recognized in the United States in patients of Asian heritage. We report on an investigation …

Risk of retinal toxicity in longterm users of hydroxychloroquine

JW Kim, YY Kim, H Lee, SH Park, SK Kim… - The Journal of …, 2017 - jrheum.org
Objective. Several studies have reported risk factors for hydroxychloroquine (HCQ) retinal
toxicity, but data are limited for patients of Asian ancestry. The aim of this study was to …

Hydroxychloroquine in lupus: emerging evidence supporting multiple beneficial effects

C Tang, T Godfrey, R Stawell… - Internal medicine …, 2012 - Wiley Online Library
Due to multiple beneficial effects, including control of disease activity, reduction in
cardiovascular events and improved survival, hydroxychloroquine is now recommended …