Gas6/TAM axis involvement in modulating inflammation and fibrosis in COVID-19 patients

M Rizzi, S Tonello, D D'Onghia… - International Journal of …, 2023 - mdpi.com
Gas6 (growth arrest-specific gene 6) is a widely expressed vitamin K-dependent protein that
is involved in many biological processes such as homeostatic regulation, inflammation and …

Adventitial cell atlas of wt (wild type) and ApoE (apolipoprotein E)-deficient mice defined by single-cell RNA sequencing

W Gu, Z Ni, YQ Tan, J Deng, SJ Zhang… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—Vascular adventitia encompasses progenitors and is getting recognized as the
major site of inflammation in early stage of atherosclerosis. However, the cellular atlas of the …

Targeting the AXL receptor in combating smoking-related pulmonary fibrosis

DC Yang, S Gu, JM Li, SW Hsu, SJ Chen… - American journal of …, 2021 - atsjournals.org
Tobacco smoking is a well-known risk factor for both fibrogenesis and fibrotic progression;
however, the mechanisms behind these processes remain enigmatic. RTKs (receptor …

Risks of Treating Idiopathic Pulmonary Fibrosis with a TAM Receptor Kinase Inhibitor

CN D'Alessandro-Gabazza, T Kobayashi… - American Journal of …, 2018 - atsjournals.org
We read with great interest the elegant work of Espindola and colleagues on the potential
beneficial effect of inhibiting TAM (Tyro3, Axl, Mer) receptor kinases in patients with …