The use of pentoxifylline, tocopherol and clodronate in the management of osteoradionecrosis of the jaws

S Patel, N Patel, I Sassoon, V Patel - Radiotherapy and Oncology, 2021 - Elsevier
Aims Medical management of osteoradionecrosis (ORN) via pentoxifylline, tocopherol
(PENTO) and clodronate (PENTOCLO) has shown both promise and early positive …

Risk factors associated with osteoradionecrosis

S Habib, I Sassoon, I Thompson, V Patel - Oral Surgery, 2021 - Wiley Online Library
Aims Risk factors have a seminal role in ORN development. Recent technological advances
such as intensity‐modulated radiation treatment (IMRT) and the rise of human papilloma …

Peri‐implant health after microvascular head and neck reconstruction—A retrospective analysis

KJ Hoffmann, C Büsch, J Moratin… - Clinical Oral …, 2024 - Wiley Online Library
Introduction Prosthodontic rehabilitation after reconstruction with microvascular
revascularized free flaps following ablative tumor surgery is challenging due to the altered …

The clinical effect of radiotherapy on pulpal microvasculature: a systematic review

R Wali, R Sacco, G Singh, V Patel - British Dental Journal, 2022 - nature.com
Introduction/objectives Radiotherapy (RT) has a detrimental effect on the histomorphology of
oral tissues. Patients undergoing RT are at risk of developing macrovascular and …

Prophylactic pentoxifylline and vitamin E use for dental extractions in irradiated patients with head and neck cancer

M Samani, S Beheshti, H Cheng, C Sproat… - Oral Surgery, Oral …, 2022 - Elsevier
Objective Osteoradionecrosis (ORN) of the jaw is preceded by dental extractions in up to
10% of cases. We present a case series of post-radiotherapy patients undergoing dental …

The use of liquid formulation pentoxifylline and vitamin E in both established and as a prophylaxis for dental extractions “at risk” of osteoradionecrosis

V Patel, H Young, A Mellor, C Sproat, J Kwok… - Oral Surgery, Oral …, 2023 - Elsevier
Background Osteoradionecrosis (ORN) of the jaws remains one of the most debilitating
complications of radiotherapy (RT) in patients with head and neck cancer (HNC). Liquid …

Dentoalveolar radiation dose following IMRT in oropharyngeal cancer—An observational study

V Patel, L Humbert‐Vidan, C Thomas… - Special Care in …, 2021 - Wiley Online Library
Objectives This observational study aims to determine individual dental doses in
oropharyngeal cancer (OPC) patients managed by intensity modulated radiation treatment …

Should the HPV positive oropharyngeal cancer patient be considered for a two-stage dental assessment for their radiation treatment?

V Patel, J Kwok, M Burke, TG Urbano… - Radiotherapy and …, 2021 - Elsevier
Patients due to commence head and neck radiation treatment are expected to undergo a
dental assessment and be deemed 'dentally fit'. Though this intervention is welcomed by the …

Genetic variants associated with mandibular osteoradionecrosis following radiotherapy for head and neck malignancy

RC Brooker, P Antczak, T Liloglou, JM Risk… - Radiotherapy and …, 2021 - Elsevier
Abstract Background/Aim Utilising radiotherapy in the management of head and neck
cancer (HNC) often results in long term toxicities. Mandibular osteoradionecrosis (ORN) …

Osteonecrosis of the jaw in primary dental care: Recognition and referral

M Burns, V Patel - Primary Dental Journal, 2022 - journals.sagepub.com
Osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ) are
uncommon conditions, however when present they have a significant impact on a patient's …