The prevalence of patients with hyperuricemia or gout is increasing worldwide.
Hyperuricemia and gout are primarily attributed to genetic factors, along with lifestyle factors …

Since glucose reuptake by neurons is mostly independent of insulin, it has been an
intriguing question whether insulin has or not any roles in the brain. Consequently, the …

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disease
characterized by involuntary bizarre movements, psychiatric symptoms, dementia, and early …

Neurodegenerative diseases, such as Alzheimer′ s disease (AD), Parkinson's disease
(PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), currently represent …

This study aimed to analyze whether taurine has a nootropic effect on short-term and long-
term memory in a model of sporadic dementia of the Alzheimer's type (SDAT). Moreover, we …

This study investigated the neuroprotective effects of exendin-4 (EXE-4), an analog of the
glucagon-like peptide 1 receptor (GLP-1R) on memory and on the neuronal populations that …

Parkinson's disease (PD) is the second most common neurodegenerative disease.
However, no curative or modifying therapy is known. Inosine is a purine nucleoside that …

Owing to renal reabsorption and the loss of uricase activity, uric acid (UA) is strictly
maintained at a higher physiological level in humans than in other mammals, which …

The nucleoside inosine is an essential metabolite for purine biosynthesis and degradation; it
also acts as a bioactive molecule that regulates RNA editing, metabolic enzyme activity, and …

Alzheimer's disease (AD) is characterized mostly by memory decline. The current
therapeutic arsenal for treating AD is limited, and the available drugs only produce …