The prevalence of fungal infections is growing at an alarming pace and the pathogenesis is
still not clearly understood. Recurrence of these fungal diseases is often due to their …

Background Honokiol is a pleiotropic compound which been isolated from Magnolia species
such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia …

Flavonoids-a class of low molecular weight secondary metabolites-are ubiquitous and
cornucopia throughout the plant kingdom. Structurally, the main structure consists of C6-C3 …

Background Cuproptosis is a newly discovered unique non-apoptotic programmed cell
death distinguished from known death mechanisms like ferroptosis, pyroptosis, and …

Glioblastoma is the deadliest form of brain cancer. Aside from inadequate treatment options,
one of the main reasons glioblastoma is so lethal is the rapid growth of tumour cells coupled …

TIMM44 (translocase of inner mitochondrial membrane 44) is essential for the maintenance
of mitochondrial functions. Bioinformatics studies and results from the local high-grade …

The human brain has high energetic expenses and consumes over 20% of total oxygen
metabolism. Abnormal brain energy homeostasis leads to various brain diseases. Among …

Glioblastoma multiforme (GBM), a highly invasive and incurable tumor, is the humans'
foremost, commonest, and deadliest brain cancer. As in other cancers, distinct combinations …

Abstract Background Coined as the “Warburg effect” and a recognized hallmark of cancer,
energy metabolism is aberrantly geared towards aerobic glycolysis in most human cancers …

Glioblastoma (GBM) is uniformly fatal with a median survival of just over 1 year, despite best
available treatment including radiotherapy (RT). Impacts of prior brain RT on recurrent …