Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

Micro RNA s (mi RNA s) have emerged as important regulators in the post‐transcriptional
control of gene expression. The discovery of their presence not only in tissues but also in …

In the last years it has become increasingly clear that the mammalian transcriptome is highly
complex and includes a large number of small non-coding RNAs (sncRNAs) and long …

Objective Genistein is a soy isoflavone that has antitumor activity both in vitro and in vivo. It
has been shown that genistein inhibits many type of cancers including prostate cancer …

CCAAT/enhancer binding protein-α (C/EBPα) induces transdifferentiation of B cells into
macrophages at high efficiencies and enhances reprogramming into induced pluripotent …

Glioblastoma (GBM) is the most prevalent primary brain tumor and ranks among the most
lethal of human cancers with conventional therapy offering only palliation. Great strides have …

Despite the fact that a large quantity of noncoding RNAs (ncRNAs) have been identified,
their functions remain unclear. To enable researchers to have a better understanding of …

miRNAs (or microRNAs) are a class of single-stranded RNA molecules, responsible for post-
transcriptional gene silencing through binding to the coding region as well as 3′ and 5 …

Post-transcriptional mechanisms have the potential to influence complex changes in gene
expression, yet their role in cell fate transitions remains largely unexplored. Here, we show …

Reprogramming, or generation of induced pluripotent stem (iPS) cells (functionally similar to
embryonic stem cells or ES cells) by the use of transcription factors (typically: Oct3/4, Sox2, c …