Surface modification strategies to improve titanium hemocompatibility: A comprehensive review

VK Manivasagam, RM Sabino, P Kantam… - Materials …, 2021 - pubs.rsc.org
Titanium and its alloys are widely used in different biomaterial applications due to their
remarkable mechanical properties and bio-inertness. However, titanium-based materials still …

Unravelling Surface Modification Strategies for Preventing Medical Device‐Induced Thrombosis

CH Luu, NT Nguyen, HT Ta - Advanced Healthcare Materials, 2024 - Wiley Online Library
The use of biomaterials in implanted medical devices remains hampered by platelet
adhesion and blood coagulation. Thrombus formation is a prevalent cause of failure of these …

Platelet-derived porous nanomotor for thrombus therapy

M Wan, Q Wang, R Wang, R Wu, T Li, D Fang… - Science …, 2020 - science.org
The treatment difficulties of venous thrombosis include short half-life, low utilization, and
poor penetration of drugs at thrombus site. Here, we develop one kind of mesoporous …

Gas station in blood vessels: An endothelium mimicking, self-sustainable nitric oxide fueling stent coating for prevention of thrombosis and restenosis

J Rao, X Mou, Y Mo, HP Bei, L Wang, CY Tang, KH Yiu… - Biomaterials, 2023 - Elsevier
Stenting is the primary treatment for vascular obstruction-related cardiovascular diseases,
but it inevitably causes endothelial injury which may lead to severe thrombosis and …

Mimicking the nitric oxide‐releasing and glycocalyx functions of endothelium on vascular stent surfaces

N Lyu, Z Du, H Qiu, P Gao, Q Yao, K Xiong… - Advanced …, 2020 - Wiley Online Library
Endothelium can secrete vasoactive mediators and produce specific extracellular matrix,
which contribute jointly to the thromboresistance and regulation of vascular cell behaviors …

[HTML][HTML] Endothelium-mimicking multifunctional coating modified cardiovascular stents via a stepwise metal-catechol-(amine) surface engineering strategy

Y Yang, P Gao, J Wang, Q Tu, L Bai, K Xiong, H Qiu… - Research, 2020 - spj.science.org
Stenting is currently the major therapeutic treatment for cardiovascular diseases. However,
the nonbiogenic metal stents are inclined to trigger a cascade of cellular and molecular …

Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release

B Zhang, R Yao, C Hu, MF Maitz, H Wu, K Liu, L Yang… - Biomaterials, 2021 - Elsevier
In-stent restenosis after stenting is generally characterized by an inflammatory response,
excessive proliferation of smooth muscle cells, and delayed healing of the endothelium …

Preparation of a heparin-like functionalized tannic acid-coated polyethersulfone ultrafiltration membrane for hemodialysis by a simple surface modification method

Z Zhang, Y Zhao, X Luo, S Feng, L Wu - Applied Surface Science, 2022 - Elsevier
It is of practical significance to develop a heparin-free hemodialysis membrane that can be
used for clinical applications in a simple way. In this work, a heparin-like coating loaded with …

A robust mussel-inspired zwitterionic coating on biodegradable poly (L-lactide) stent with enhanced anticoagulant, anti-inflammatory, and anti-hyperplasia properties

L Yang, H Wu, Y Liu, Q Xia, Y Yang, N Chen… - Chemical Engineering …, 2022 - Elsevier
Endowing cardiovascular stents with multiple functionalities, such as anti–proliferative, and
anti–inflammatory properties, is important for combating restenosis after stent implantation …

Green Tea Polyphenol Induced Mg2+-rich Multilayer Conversion Coating: Toward Enhanced Corrosion Resistance and Promoted in Situ Endothelialization of AZ31 …

B Zhang, R Yao, L Li, Y Wang, R Luo… - … applied materials & …, 2019 - ACS Publications
As a promising biodegradable metallic material, magnesium (Mg) and its alloys have
attracted special attention in the recent decade. However, challenges still remain due to its …