Imidazole: synthesis, functionalization and physicochemical properties of a privileged structure in medicinal chemistry

HV Tolomeu, CAM Fraga - Molecules, 2023 - mdpi.com
Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction
of glyoxal and formaldehyde in ammonia, initially called glyoxaline. The current literature …

Organophosphorus chemical security from a peaceful perspective: Sustainable practices in its synthesis, decontamination and detection

VB Silva, YH Santos, R Hellinger, S Mansour… - Green …, 2022 - pubs.rsc.org
Organophosphorus compounds play an important role in the modern chemical industry and
have a broad range of applications as flame retardants, agrochemicals, and chemical …

Nucleophilic neutralization of organophosphates: lack of selectivity or plenty of versatility?

VB Silva, RB Campos, P Pavez… - The Chemical …, 2021 - Wiley Online Library
Neutralization of organophosphates is an issue of public health and safety, involving
agrochemicals and chemical warfare. A promising approach is the nucleophilic …

Imidazole-derived graphene nanocatalysts for organophosphate destruction: Powder and thin film heterogeneous reactions

L Hostert, SF Blaskievicz, JES Fonsaca… - Journal of …, 2017 - Elsevier
Promoting efficient organophoshate (OP) destruction has been of increasing interest, mainly
due to their highly toxic nature and broad use as agrochemicals and chemical warfare. It is …

Co3O4/Reduced Graphene Oxide Nanocomposites as Effective Phosphotriesterase Mimetics for Degradation and Detection of Paraoxon

T Wang, J Wang, Y Yang, P Su… - Industrial & Engineering …, 2017 - ACS Publications
In this work, Co3O4 nanoparticles supported on reduced graphene oxide (Co3O4/rGO) were
prepared through a simple hydrothermal method. The phosphotriesterase (PTE) mimetic …

Magnetic nanocatalysts derived from carbon nanotubes functionalized with imidazole: towards pesticide degradation

SF Blaskievicz, WG Endo, AJG Zarbin… - Applied catalysis B …, 2020 - Elsevier
The cleavage of highly toxic organophoshates (OP) can lead to products of a reduced
toxicity, and due to this, materials and routes to promote efficiently this reaction has been of …

Soft detoxification of chemical warfare agent simulants and pesticides under pressure

S Mansour, VB Silva, ES Orth, J Legros - Organic & Biomolecular …, 2022 - pubs.rsc.org
The neutralisation of structurally varied chemical warfare agent simulants (blister and nerve
agents) and pesticides (Paraoxon) with the assistance of high pressure is reported …

Transesterification of RNA model induced by novel dinuclear copper (II) complexes with bis-tridentate imidazole derivatives

X Wang, J Shu, T Ni, C Xu, B Xu, X Liu, K Zhang… - JBIC Journal of …, 2023 - Springer
Two novel bis-tridentate imidazole derivatives were conveniently synthesized using a 'one-
pot'method. Their dinuclear (Cu2L1Cl4, Cu2L2Cl4) and mononuclear (CuL1Cl2, CuL2Cl2∙ …

Waste-derived biocatalysts for pesticide degradation

JGL Ferreira, WH Takarada, ES Orth - Journal of Hazardous Materials, 2022 - Elsevier
A green approach to produce a cellulose-derived biocatalyst containing hydroxamic acids
targeted for the neutralization of toxic organophosphates is shown. The cellulose source …

Tailoring multifunctional graphene-based thin films: from nanocatalysts to SERS substrates

JES Fonsaca, L Hostert, ES Orth… - Journal of Materials …, 2017 - pubs.rsc.org
Anchoring different functional groups on graphene may modulate and broaden its
application, providing free groups to act for example as catalytic sites or for metallic …