Imaginal disc regeneration: something old, something new

MI Worley, IK Hariharan - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
Imaginal discs are simple epithelial sacs found in Drosophila larvae, which generate adult
structures including wings and legs. The first studies of imaginal disc regeneration involved …

Cellular and Molecular Triggers of Retinal Regeneration in Amphibians

YV Markitantova, EN Grigoryan - Life, 2023 - mdpi.com
Understanding the mechanisms triggering the initiation of retinal regeneration in amphibians
may advance the quest for prevention and treatment options for degenerating human retina …

Hydra gasdermin-gated pyroptosis signalling regulates tissue regeneration

S Chen, Y Gong, S Li, D Yang, Y Zhang… - Developmental & …, 2023 - Elsevier
Pyroptosis, an inflammatory form of programmed cell death, is directly executed by
gasdermin (GSDM) depending on its N-terminal pore-forming fragment-mediated membrane …

Nuclear reassembly defects after mitosis trigger apoptotic and p53-dependent safeguard mechanisms in Drosophila

J Li, L Jordana, H Mehsen, X Wang… - PLoS biology, 2024 - journals.plos.org
In animals, mitosis involves the breakdown of the nuclear envelope and the sorting of
individualized, condensed chromosomes. During mitotic exit, emerging nuclei reassemble a …

A missense mutation in human INSC causes peripheral neuropathy

JY Yeh, HC Chao, CL Hong, YC Hung… - EMBO Molecular …, 2024 - embopress.org
Abstract PAR3/INSC/LGN form an evolutionarily conserved complex required for asymmetric
cell division in the developing brain, but its post-developmental function and disease …

Caspases promote cell proliferation after necrosis

P Yarikipati, A Bergmann - eLife, 2024 - elifesciences.org
Cell Death: Caspases promote cell proliferation after necrosis | eLife Skip to Content eLife logo
eLife home page Menu Home Magazine Community About Search Alerts Submit your …

Understanding the molecular mechanism of regeneration through apoptosis-induced compensatory proliferation studies-updates and future aspects

K Rajagopalan, JD Selvan Christyraj, KS Chelladurai… - Apoptosis, 2024 - Springer
AICP is a crucial process that maintaining tissue homeostasis and regeneration. In the past,
cell death was perceived merely as a means to discard cells without functional …

[HTML][HTML] Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

J Klemm, C Van Hazel, R Harris - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Tissue necrosis is a devastating complication for many human diseases and injuries.
Unfortunately, our understanding of necrosis and how it impacts surrounding healthy tissue …

The correlation between plasma circulating tumor DNA and radiographic tumor burden

EM Alexander, HA Miller, ME Egger, ML Smith… - The Journal of Molecular …, 2024 - Elsevier
Traditional blood-based biomarkers and radiographic imaging excel at different aspects of
monitoring malignant disease, but given their specific shortcomings, their integration with …

Regenerative Strategies for Retinal Neurons: Novel Insights in Non-Mammalian Model Organisms

E Catalani, A Cherubini, S Del Quondam… - International Journal of …, 2022 - mdpi.com
A detailed knowledge of the status of the retina in neurodegenerative conditions is a crucial
point for the development of therapeutics in retinal pathologies and to translate eye research …