Mucosal applications of poloxamer 407-based hydrogels: An overview

E Giuliano, D Paolino, M Fresta, D Cosco - Pharmaceutics, 2018 - mdpi.com
Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …

A review of poloxamer 407 pharmaceutical and pharmacological characteristics

G Dumortier, JL Grossiord, F Agnely… - Pharmaceutical …, 2006 - Springer
Abstract Poloxamer 407 copolymer (ethylene oxide and propylene oxide blocks) shows
thermoreversible properties, which is of the utmost interest in optimising drug formulation …

In situ-forming hydrogels—review of temperature-sensitive systems

E Ruel-Gariepy, JC Leroux - European Journal of Pharmaceutics and …, 2004 - Elsevier
In the past few years, an increasing number of in situ-forming systems have been reported in
the literature for various biomedical applications, including drug delivery, cell encapsulation …

[图书][B] Bubbles, drops, and particles in non-Newtonian fluids

RP Chhabra - 2006 - taylorfrancis.com
Bubbles, Drops, and Particles in Non-Newtonian Fluids, Second Edition continues to
provide thorough coverage of the scientific foundations and the latest advances in particle …

Mucoadhesive and thermogelling systems for vaginal drug delivery

CM Caramella, S Rossi, F Ferrari, MC Bonferoni… - Advanced drug delivery …, 2015 - Elsevier
This review focuses on two formulation approaches, mucoadhesion and thermogelling,
intended for prolonging residence time on vaginal mucosa of medical devices or drug …

Pluronic F-68 and F-127 based nanomedicines for advancing combination cancer therapy

NU Khaliq, J Lee, S Kim, D Sung, H Kim - Pharmaceutics, 2023 - mdpi.com
Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene
oxide)(PEO) chains linked via a central hydrophobic polypropylene oxide (PPO). Owing to …

Thixotropic property in pharmaceutical formulations

CH Lee, V Moturi, Y Lee - Journal of controlled release, 2009 - Elsevier
This review focuses on the characterization of the thixotropic property, the factors affecting
the thixotropic property and its pharmaceutical applications. These factors include pH …

New strategies for local treatment of vaginal infections

R Palmeira-de-Oliveira, A Palmeira-de-Oliveira… - Advanced drug delivery …, 2015 - Elsevier
Vaginal infections are extremely prevalent, particularly among women of reproductive age.
Although they do not result in high mortality rates, these infections are associated with high …

Recent advances in polymer-based vaginal drug delivery systems

T Osmałek, A Froelich, B Jadach, A Tatarek… - Pharmaceutics, 2021 - mdpi.com
The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …

Gels as vaginal drug delivery systems

J Das Neves, MF Bahia - International journal of Pharmaceutics, 2006 - Elsevier
The vagina has been used as a mucosal drug delivery route for a long time. Its single
characteristics can be either limitative or advantageous when drug delivery is considered …