Loss of LOXL2 promotes uterine hypertrophy and tumor progression by enhancing H3K36ac-dependent gene expression

X Lu, DE Xin, JK Du, QC Zou, Q Wu, YS Zhang… - Cancer research, 2022 - AACR
Abstract Lysyl oxidase-like 2 (LOXL2) is a member of the scavenger receptor cysteine-rich
(SRCR) repeat carrying LOX family. Although LOXL2 is suspected to be involved in histone …

A click chemistry approach reveals the chromatin-dependent histone H3K36 deacylase nature of SIRT7

WW Wang, M Angulo-Ibanez, J Lyu… - Journal of the …, 2019 - ACS Publications
Using an engineered pyrrolysyl-tRNA synthetase mutant together with tRNACUAPyl, we
have genetically encoded Nε-(7-azidoheptanoyl)-l-lysine (AzHeK) by amber codon in …

The Chromatin Remodeler and Tumor Suppress Chd5 Promotes Expression and Processing of Transcripts During Development of the Zebrafish Neural System

E Sorlien - 2019 - search.proquest.com
Vertebrate neurogenesis is a multistep process that coordinates complex signaling
pathways and chromatin-based regulatory machinery to generate highly specialized cells …