Accumulating evidence indicates that most primary Wharton's jelly mesenchymal stem cells
(WJ-MSCs) therapeutic potential is due to their paracrine activity, ie, their ability to modulate …

Diabetic nephropathy (DN) is one of the most common diabetes mellitus (DM) microvascular
complications, which always ends with end-stage renal disease (ESRD). Up to now, as the …

Mesenchymal stem/stromal cells (MSCs) represent a heterogeneous cell population
distributed throughout various tissues, demonstrating remarkable adaptability to …

Paracrine factors secreted by mesenchymal stem cells (MSCs) reportedly modulate
inflammation and reparative processes in damaged tissues and have been explored for …

Obesity is characterized by chronic low-grade inflammation. Obese people have higher
levels of caveolin-1 (CAV1), a structural and functional protein present in adipose tissues …

Rationale: Glioma stem cells (GSCs) have emerged as pivotal drivers of tumor malignancy,
sustained by various microenvironmental factors, including immune molecules and hypoxia …

This study unveils verapamil's compelling cytoprotective and proliferative effects on
pancreatic β-cells amidst diabetic stressors, spotlighting its unforeseen role in augmenting …

The imipramine ONC201 has antiproliferative effects in several cancer cell types and
activates integrated stress response pathway associated with the induction of Damage …

Liver diseases are major causes of morbidity and mortality. Dental pulp pluripotent‐like stem
cells (DPPSCs) are of a considerable promise in tissue engineering and regenerative …

Caveolin-1 (CAV1) is implicated in the pathophysiology of diabetes and obesity. Previously,
we demonstrated an association between the CAV1 rs1997623 C> A variant and metabolic …