Differential diagnosis of suspected multiple sclerosis: an updated consensus approach

AJ Solomon, G Arrambide, WJ Brownlee… - The Lancet …, 2023 - thelancet.com
Accurate diagnosis of multiple sclerosis requires careful attention to its differential diagnosis—
many disorders can mimic the clinical manifestations and paraclinical findings of this …

Pathophysiology of myelin oligodendrocyte glycoprotein antibody disease

O Corbali, T Chitnis - Frontiers in Neurology, 2023 - frontiersin.org
Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD) is a spectrum of diseases,
including optic neuritis, transverse myelitis, acute disseminated encephalomyelitis, and …

Timing of MOG-IgG testing is key to 2023 MOGAD diagnostic criteria

M Forcadela, C Rocchi, D San Martin… - Neurology …, 2023 - AAN Enterprises
Background and Objectives Myelin oligodendrocyte glycoprotein (MOG) antibody–
associated disease (MOGAD) is a recently identified autoimmune demyelinating disorder of …

NMOSD and MOGAD: an evolving disease spectrum

A Uzawa, FC Oertel, M Mori, F Paul… - Nature Reviews …, 2024 - nature.com
Neuromyelitis optica (NMO) spectrum disorder (NMOSD) is a relapsing inflammatory
disease of the CNS, characterized by the presence of serum aquaporin 4 (AQP4) …

Myelitis features and outcomes in CNS demyelinating disorders: comparison between multiple sclerosis, MOGAD, and AQP4-IgG-positive NMOSD

G Fadda, EP Flanagan, L Cacciaguerra… - Frontiers in …, 2022 - frontiersin.org
Inflammatory myelopathies can manifest with a combination of motor, sensory and
autonomic dysfunction of variable severity. Depending on the underlying etiology, the …

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): current understanding and challenges

A Al-Ani, JJ Chen, F Costello - Journal of Neurology, 2023 - Springer
New diagnostic criteria for myelin oligodendrocyte glycoprotein antibody-associated disease
(MOGAD) have recently been proposed, distinguishing this syndrome from other …

An autoantibody signature predictive for multiple sclerosis

CR Zamecnik, GM Sowa, A Abdelhak, R Dandekar… - Nature Medicine, 2024 - nature.com
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or
diagnostic autoantibody remains elusive. In this study, the Department of Defense Serum …

Neuroimaging features in inflammatory myelopathies: a review

L Cacciaguerra, E Sechi, MA Rocca, M Filippi… - Frontiers in …, 2022 - frontiersin.org
Spinal cord involvement can be observed in the course of immune-mediated disorders.
Although multiple sclerosis (MS) represents the leading cause of inflammatory myelopathy …

[HTML][HTML] Astrocyte-Mediated Neuroinflammation in Neurological Conditions

Y Zhao, Y Huang, Y Cao, J Yang - Biomolecules, 2024 - mdpi.com
Astrocytes are one of the key glial types of the central nervous system (CNS), accounting for
over 20% of total glial cells in the brain. Extensive evidence has established their …

Diagnostic Utility of MOG Antibody Testing in Cerebrospinal Fluid

V Redenbaugh, JP Fryer, L Cacciaguerra… - Annals of …, 2024 - Wiley Online Library
Objective The aim of this study was to assess the diagnostic utility of cerebrospinal fluid
(CSF) myelin oligodendrocyte glycoprotein antibodies (MOG‐IgG) testing. Methods We …