Hypophysitis is an inflammation of the pituitary gland and is a rare cause of hypopituitarism.
It can be primary (idiopathic) or secondary to sella and parasellar lesions, systemic …

Central or neurogenic diabetes insipidus (CDI) is due to deficient synthesis or secretion of
antidiuretic hormone (ADH), also known as arginine vasopressin peptide (AVP). It is …

PURPOSE Childhood brain tumor survivors (CBTS) are at risk for developing obesity, which
negatively influences cardiometabolic health. The prevalence of obesity in CBTS may have …

Opinion statement Pathologies of pediatric brain tumors are more varied than those
diagnosed in adults and survival outcomes more optimistic. Therapies for pediatric brain …

Hypoprolactinaemia is an endocrinopathy which is typically encountered as part of a
combined pituitary hormone deficiency picture. The vast majority of genetic causes identified …

Hypopituitarism in childhood is a rare, complex disorder that can present with highly variable
phenotypes, which may continue into adult life. Pituitary deficits can evolve over time, with …

The purpose of this work was to present the current state of knowledge on the effects of
frequently used therapeutic forms, selected pharmacotherapy (including …

Tumours of the central nervous system (CNS) represent the most common group of solid
tumours in children and adolescents up to the age of 18 years. They comprise several …

Central diabetes insipidus (CDI) occurs secondary to deficient synthesis or secretion of
arginine vasopressin peptide from the hypothalamo–neurohypophyseal system (HNS). It is …

Purpose BRAF and MEK inhibitors are used to treat a range of paediatric tumours including
low-grade gliomas. The ubiquitous nature of the BRAF/MAPK/MEK pathway means such …