Medication overuse in primary headache disorders is a worldwide phenomenon and has a
role in the chronification of headache disorders. The burden of disease on individuals and …

Chronic migraine is a disabling neurologic condition that affects 2% of the general
population. Patients with chronic migraine have headaches on at least 15 days a month …

Background Neurological disorders are increasingly recognised as major causes of death
and disability worldwide. The aim of this analysis from the Global Burden of Diseases …

Background Clinical trials have shown the safety and clinical superiority of erenumab
compared to placebo in chronic migraine (CM). The aim of this analysis is to evaluate the …

Objective To evaluate the relationships among modifiable psychological factors and chronic
migraine and severe migraine‐related disability in a clinic‐based sample of persons with …

Background: The effectiveness of greater occipital nerve block (GONB) in patients with
primary headache syndromes is controversial. Few studies have been evaluated the …

Migraine is a highly prevalent headache disease that typically affects patients during their
most productive years. Despite significant progress in understanding the underlying …

The term refractory migraine has been used to describe persistent headache that is difficult
to treat or fails to respond to standard and/or aggressive treatments. This subgroup of …

Background Chronic migraine is a debilitating headache disorder that has significant impact
on quality of life. Stimulation of peripheral nerves is increasingly being used to treat chronic …

Abstract Purpose of Review Chronic headaches are a significant source of disability
worldwide. Despite the development of conventional strategies, a subset of patients remain …