Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Structural diversity and biological activities of phloroglucinol derivatives from Hypericum species

H Bridi, G de Carvalho Meirelles, GL von Poser - Phytochemistry, 2018 - Elsevier
Plants of the genus Hypericum (Hypericaceae) are used in folk medicine all over the world,
H. perforatum being the most well-known species. Standardized extracts of this plant are …

Investigation of the anti-inflammatory effects of stigmasterol in mice: insight into its mechanism of action

LV Morgan, F Petry, M Scatolin… - Behavioural …, 2021 - journals.lww.com
Stigmasterol is a phytosterol that presents pharmacologic properties. However, its anti-
inflammatory mechanism and antinociceptive effect are not yet elucidated. Thus, the present …

Medicinal plants in the treatment of depression: Evidence from preclinical studies

I Moragrega, JL Ríos - Planta medica, 2021 - thieme-connect.com
Medicinal plants and their extracts are natural remedies with enormous potential for treating
various diseases, including depression and anxiety. In the case of depression, hundreds of …

Endogenous opiates and behavior: 2012

RJ Bodnar - Peptides, 2013 - Elsevier
This paper is the thirty-fifth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2012 …

Methylene-bridged dimeric natural products involving one-carbon unit in biosynthesis

Y Fan, J Shen, Z Liu, K Xia, W Zhu, P Fu - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to February 2022 Naturally occurring dimeric molecules attract considerable
attention from both chemists and biologists. The methylene-bridged dimers with one-carbon …

[HTML][HTML] Stress induction of valuable secondary metabolites in Hypericum polyanthemum acclimatized plants

J de Matos Nunes, LOO Bertodo, LMG Da Rosa… - South African Journal of …, 2014 - Elsevier
Uliginosin B, an antidepressant-like phloroglucinol derivative, three benzopyrans and total
phenolic compounds (TPC) of flowering Hypericum polyanthemum acclimatized plants were …

Dimeric acylphloroglucinols in Hypericum species from sections Brathys and Trigynobrathys

GV Ccana-Ccapatinta, FMC de Barros, H Bridi… - Phytochemistry …, 2015 - Springer
Hypericum is a prolific source of acylphloroglucinol derivatives. Unlike the monomeric
polyisoprenylated acylphloroglucinols hyperforin and adhyperforin, which are the main …

The Phytochemistry and Pharmacology of Hypericum

CY Xiao, Q Mu, S Gibbons - Progress in the chemistry of organic natural …, 2020 - Springer
Hypericum L. is a genus of the family Hypericaceae within the dicotyledones. The
constituents of Hypericum species are valued for their important biological properties. Their …

Effects of UV-B radiation on total phenolic, flavonoid and hypericin contents in Hypericum retusum Aucher grown under in vitro conditions

S Namlı, Ç Işıkalan, F Akbaş, Z Toker… - Natural Product …, 2014 - Taylor & Francis
This study was conducted to increase total phenolics, flavonoids and hypericin accumulation
in in vitro cultures of Hypericum retusum Aucher to determine the appropriate time of UV …