The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Due to its built-up chemoresistance after prolonged usage, the demand for replacing
platinum in metal-based drugs (MBD) is rising. The first MBD approved by the FDA for …

Nuxia oppositifolia is traditionally used in diabetes treatment in many Arabian countries;
however, scientific evidence is lacking. Hence, the present study explored the antidiabetic …

Cancer is a heterogeneous and multifactorial disease that causes high mortality throughout
the world; therefore, finding the most effective therapies is a major research challenge …

Copper is an essential element for most aerobic organisms, with an important function as a
structural and catalytic cofactor, and in consequence, it is implicated in several biological …

Developing new, smart drugs with the anticancer activity is crucial, especially for cancers,
which cause the highest mortality in humans. In this paper we describe a series of …

Thiazolidinedione derivatives (TZDs) have attracted attention because of their
pharmacological effects. For example, certain TZDs have been reported to ameliorate type II …

Discovery of 99m Tc-labeled imidazole derivatives as a potential radiotracer for hypoxic
tumor imaging is considered to be of great interest because of non-invasive detection …

Benzimidazoles are a class of heterocyclic, aromatic compounds which share a fundamental
structural characteristic of six-membered benzene fused to fivemembered imidazole moiety …

In this study, a series of 14 Cu (II), Zn (II), Ni (II) and Ag (I) complexes containing bis-
benzimidazole derivatives were successfully designed and synthesized from 2-(1 H …