Particle sizes of infectious aerosols: implications for infection control

KP Fennelly - The Lancet Respiratory Medicine, 2020 - thelancet.com
The global pandemic of COVID-19 has been associated with infections and deaths among
health-care workers. This Viewpoint of infectious aerosols is intended to inform appropriate …

Respiratory aerosols and droplets in the transmission of infectious diseases

ML Pöhlker, C Pöhlker, OO Krüger, JD Förster… - Reviews of Modern …, 2023 - APS
Knowing the physicochemical properties of exhaled droplets and aerosol particles is a
prerequisite for a detailed mechanistic understanding and effective prevention of the …

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection

JD Simmons, CM Stein, C Seshadri, M Campo… - Nature Reviews …, 2018 - nature.com
Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a
long-lived latent infection in a substantial proportion of the human population. Multiple lines …

Point-of-care diagnostic tests for tuberculosis disease

JM Hong, H Lee, NV Menon, CT Lim, LP Lee… - Science translational …, 2022 - science.org
Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs)
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …

Exhaled Mycobacterium tuberculosis output and detection of subclinical disease by face-mask sampling: prospective observational studies

CM Williams, M Abdulwhhab, SS Birring… - The Lancet Infectious …, 2020 - thelancet.com
Background Tuberculosis remains a global health challenge, with early diagnosis key to its
reduction. Face-mask sampling detects exhaled Mycobacterium tuberculosis. We aimed to …

[HTML][HTML] Is cough really necessary for TB transmission?

B Patterson, R Wood - Tuberculosis, 2019 - Elsevier
Cough has long been implicated in the production of infectious aerosol leading to
transmission of tuberculosis (TB). However, prevalence studies frequently identify …

Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights

M Coleman, L Martinez, G Theron, R Wood, B Marais - Pathogens, 2022 - mdpi.com
Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …

Aerosolization of Mycobacterium tuberculosis by Tidal Breathing

R Dinkele, S Gessner, A McKerry… - American Journal of …, 2022 - atsjournals.org
Rationale: Interrupting tuberculosis (TB) transmission requires an improved understanding
of how and when the causative organism, Mycobacterium tuberculosis (Mtb), is aerosolized …

A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis detection

SF Mosquera-Restrepo, S Zuberogoïtia… - Nature …, 2022 - nature.com
An estimated one-third of tuberculosis (TB) cases go undiagnosed or unreported. Sputum
samples, widely used for TB diagnosis, are inefficient at detecting infection in children and …

Droplet digital PCR applications in the tuberculosis world

R Nyaruaba, C Mwaliko, KK Kering, H Wei - Tuberculosis, 2019 - Elsevier
Droplet digital polymerase chain reaction (ddPCR) is a third generation of polymerase chain
reaction (PCR) that enables the exact quantification of nucleic acid targets within a sample …