Functional characterization of co-phosphorylation networks
Motivation Protein phosphorylation is a ubiquitous regulatory mechanism that plays a central
role in cellular signaling. According to recent estimates, up to 70% of human proteins can be …
role in cellular signaling. According to recent estimates, up to 70% of human proteins can be …
Augmenting signaling pathway reconstructions
Signaling pathways drive cellular response, and understanding such pathways is
fundamental to molecular systems biology. A mounting volume of experimental protein …
fundamental to molecular systems biology. A mounting volume of experimental protein …
Growing Directed Acyclic Graphs: Optimization Functions for Pathway Reconstruction Algorithms
TB Köse, J Li, A Ritz - Journal of Computational Biology, 2023 - liebertpub.com
A major challenge in molecular systems biology is to understand how proteins work to
transmit external signals to changes in gene expression. Computationally reconstructing …
transmit external signals to changes in gene expression. Computationally reconstructing …
The international conference on intelligent biology and medicine 2019 (ICIBM 2019): conference summary and innovations in genomics
The goal of this editorial is to summarize the 2019 International Conference on Intelligent
Biology and Medicine (ICIBM 2019) conference that took place on June 9–11, 2019 in The …
Biology and Medicine (ICIBM 2019) conference that took place on June 9–11, 2019 in The …
Growing DAGs: Optimization Functions for Pathway Reconstruction Algorithms
TB Köse, J Li, A Ritz - bioRxiv, 2022 - biorxiv.org
A major challenge in molecular systems biology is to understand how proteins work to
transmit external signals to changes in gene expression. Computationally reconstructing …
transmit external signals to changes in gene expression. Computationally reconstructing …
Constructing Functional Networks of Phosphorylation Sites Using Co-Phosphorylation
Protein phosphorylation is a ubiquitous regulatory mechanism that plays a central role in
cellular signaling. According to recent estimates, up to 70% of human proteins can be …
cellular signaling. According to recent estimates, up to 70% of human proteins can be …