Background Optimal vitamin D intake and its status are important not only for bone and
calcium-phosphate metabolism, but also for overall health and well-being. Vitamin D …

The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …

Aging can be seen as a physiological progression of biomolecular damage and the
accumulation of defective cellular components, which trigger and amplify the process …

Besides its actions on minerals and bone, the bioactive vitamin D metabolite, 1, 25-
dihydroxyvitamin D3 (1, 25 (OH) 2D3), has important immunomodulatory properties. Within …

Objective To examine the immunologic mechanism by which 1, 25‐dihydroxyvitamin D3 (1,
25 [OH] 2D3) may prevent corticosteroid‐induced osteoporosis in patients with early …

Vitamin D is a secosteroid hormone that is highly involved in bone health. Mounting
evidence revealed that, in addition to the regulation of mineral metabolism, vitamin D is …

Naïve CD4+ helper T (TH) cells, upon activation by antigen‐presenting cells (APC),
differentiate into different types of effector cells that are characterized by their distinct …

The effects of vitamin D on the immune function have been recognized for more than a
quarter of a century. However, our understanding of the multifactorial nature of the effects of …

Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology.
Besides the canonical regulatory activity on bone metabolism, several non-classical actions …

Results Clinical characteristics in GD patients and control subjects were shown in Table 1.
All serum TSH levels, and FT3 and FT4 levels in GD patients were below 0.01 μIU/ml and …