Diabetic retinopathy (DR) is a microvascular complication associated with chronic exposure
to hyperglycemia and is a major cause of blindness worldwide. Although clinical …

Diabetic retinopathy (DR) is a multifactorial progressive disease of the retina and a leading
cause of vision loss. DR has long been regarded as a vascular disorder, although neuronal …

Purpose: Electroretinograms (ERGs) are abnormal in diabetic retinas before the appearance
of vascular lesions, providing a possible biomarker for diabetic vision loss. Previously, we …

Diabetes leads to dysfunction of the neural retina before and independent of classical
microvascular diabetic retinopathy, but previous studies have failed to demonstrate which …

Purpose Diabetic retinopathy is a neurovascular disease characterized by increased
permeability of the blood–retinal barrier, changes in the neural components of the retina …

Background: Diabetic retinopathy (DR) is a major complication of diabetes, characterized by
extensive vascular pathology leading to vision loss. Neuronal suffering and death are also …

Purpose: The balance of neuronal excitation and inhibition is important for proper retinal
signaling. A previous report showed that diabetes selectively reduces light-evoked inhibition …

Experimental models of diabetic retinopathy (DR) have had a crucial role in the
comprehension of the pathophysiology of the disease and the identification of new …

One of the tissues of the central nervous system most affected by diabetes is the retina.
Despite a growing understanding of the biochemical processes involved in glucose toxicity …

There is increasing evidence that diabetic retinopathy is a primary neuropathological
disorder that precedes the microvascular pathology associated with later stages of the …