Pharmacogenetics of antipsychotic drug treatment: update and clinical implications

K Yoshida, DJ Müller - Complex Psychiatry, 2019 - karger.com
Numerous genetic variants have been shown to be associated with antipsychotic response
and adverse effects of schizophrenia treatment. However, the clinical application of these …

Antipsychotic-induced hyperprolactinemia in aging populations: prevalence, implications, prevention and management

A González-Rodríguez, J Labad, MV Seeman - Progress in Neuro …, 2020 - Elsevier
This paper reviews the prevalence, implications, prevention and management of
antipsychotic-induced hyperprolactinemia in aging populations. Antipsychotics are indicated …

Association between BDNF gene variant Rs6265 and the severity of depression in antidepressant treatment-free depressed patients

IS Losenkov, NJV Mulder, LA Levchuk… - Frontiers in …, 2020 - frontiersin.org
Background Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal
plasticity, and its dysregulation has been associated with the pathogenesis of mood and …

A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia

DZ Osmanova, MB Freidin, OY Fedorenko… - BMC Medical …, 2019 - Springer
Background Hyperprolactinemia (HPRL) is a classical side effect of antipsychotic drugs
primarily attributed to blockade of dopamine D2 receptors (DRD2s) on the membranes of …

Hyperprolactinemia and insulin resistance in drug naive patients with early onset first episode psychosis

MG Petruzzelli, M Margari, A Peschechera… - BMC psychiatry, 2018 - Springer
Background Hyperprolactinemia and glucose and lipid metabolism abnormalities are often
found in patients with schizophrenia and are generally considered secondary to the use of …

Investigating the potential role of BDNF and PRL genotypes on antidepressant response in depression patients: a prospective inception cohort study in treatment-free …

T Ochi, NM Vyalova, IS Losenkov, LA Levchuk… - Journal of Affective …, 2019 - Elsevier
Background Brain-derived neurotrophic factor (BDNF) is associated with response to
antidepressant drugs in mood and anxiety disorders. Prolactin (PRL) is a pituitary hormone …

Protective Effect of Hyperprolactinemia on Oxidative Stress in Patients with Psychotic Disorder on Atypical Antipsychotics Risperidone and Paliperidone: A Cross …

M Stojkovic, M Jovanovic, V Jakovljevic, V Zivkovic… - Biomedicines, 2024 - mdpi.com
Several studies indicate the impact of antipsychotics like risperidone and paliperidone on
oxidative stress parameters, yet data remain inconsistent. We investigated the link between …

Opening up new horizons for psychiatric genetics in the Russian Federation: moving toward a national consortium

OY Fedorenko, VE Golimbet, SА Ivanova… - Molecular …, 2019 - nature.com
We provide an overview of the recent achievements in psychiatric genetics research in the
Russian Federation and present genotype-phenotype, population, epigenetic, cytogenetic …

Association between 8 P‐glycoprotein (MDR1/ABCB1) gene polymorphisms and antipsychotic drug‐induced hyperprolactinaemia

LM Geers, IV Pozhidaev, SA Ivanova… - British journal of …, 2020 - Wiley Online Library
Introduction Hyperprolactinaemia, a common adverse effect of antipsychotic drugs, is
primarily linked to blockade of dopamine D2 receptors in the pituitary gland. Certain …

CLASH-VLT: a full dynamical reconstruction of the mass profile of Abell S1063 from 1 kpc out to the virial radius

B Sartoris, A Biviano, P Rosati, A Mercurio… - Astronomy & …, 2020 - aanda.org
Context. The shape of the mass density profiles of cosmological halos informs us of the
nature of dark matter (DM) and DM-baryons interactions. Previous estimates of the inner …