Conjugated α, β-unsaturated ketones are very useful compounds associated with diverse
medicinal properties. This review outlines α, β-unsaturated ketones as candidate cytotoxic …

Several studies have documented the ability of flavonoids to sensitize cancer cells to
chemotherapeutics and reverse multidrug resistance by inhibition of efflux pumps …

The synthesis and anticancer evaluation of novel selenium-nonsteroidal anti-inflammatory
drug (Se-NSAID) hybrid molecules are reported. The Se-aspirin analogue 8 was identified …

Genistein, a dietary polyphenol primarily found in soy products, has beneficial effects on
bone. However, the effect of genistein on inflammatory periodontal destruction has not been …

In this review, we summarize pyrroloquinoline and pyrroloisoquinoline derivatives (PQs and
PIQs) that act on a broad spectrum of biological targets and are used as bacteriostatic …

Background/Aims: MicroRNAs (miRNAs) play an essential role in the tumorigenesis of
gastric carcinoma (GC). MiR-429 has been recently reported to inhibit GC growth, but the …

Many reports have shown the anticancer effects of iron deficient on cancer cells, but the
effects of iron-chelators on gastric cancer have not been clearly elucidated. Recently, we …

Background/Aims: ER-Stress and activation of unfolded protein response belong to the
major factors involved in chemoresistance in cancer cells. In this study we investigated the …

Background/Aims: Acute myeloid leukemia (AML) is a heterogeneous clonal disease and
patients with AML who harbor an FMS-like tyrosine kinase 3 (FLT3) mutation present several …

Background/Aims: Acute and chronic leukemia are severe malignant cancers worldwide,
and can occur in pediatric patients. Since bone marrow cell transplantation is seriously …