Over the past decades Raman spectroscopy has been extensively used both on an
industrial and academic level. This has resulted in the development of numerous …

Paracetamol is a popular antipyretic and analgesic active pharmaceutical ingredient that is
used worldwide in the production of several millions of tablets and other dosage forms every …

A substance can crystallize in more than one crystal form. This phenomenon, known as
polymorphism, occurs particularly often for organic compounds because of the comparable …

The multiparameter model comprising 1D and 2D QSPR/QSAR descriptors was proposed
and validated for phenolic acid binary systems. This approach is based on the optimization …

A directional crystallization of the compound 2, 7-dioctyl [1] benzothieno [3, 2-b][1]
benzothiophene (C8-BTBT-C8) based on a temperature gradient approach has been used …

(R, S)-2-Chloromandelic acid, which can crystallize in racemic crystals (forms α and β) or a
conglomerate (form γ), has been studied for its glass-forming behavior. Below the glass …

We revisit the polymorphism of paracetamol by means of a micro-Raman technique, which
has proved to be a powerful tool for structure recognition. Distinct lattice phonon spectra …

We have demonstrated the directional lateral crystallization of thin film C8-BTBT which is pre-
vacuum-deposited on a SiO2/Si substrate, with good controllability of the crystallization rate …

Spherical agglomeration (SA) is a novel process intensification strategy for particulate
manufacturing. In the context of pharmaceutical manufacturing, it has the potential to reduce …

A high percentage of active pharmaceutical ingredient are available in the insoluble
crystalline phase. During pharmaceutical processing such as milling there are many issues …