Microbiome as a therapeutic target in alcohol-related liver disease

SK Sarin, A Pande, B Schnabl - Journal of hepatology, 2019 - Elsevier
Alcohol-related liver disease is associated with significant changes in gut microbial
composition. The transmissibility of ethanol-induced liver disease has been demonstrated …

Alcohol or gut microbiota: who is the guilty?

M Meroni, M Longo, P Dongiovanni - International journal of molecular …, 2019 - mdpi.com
Alcoholic liver disease (ALD), a disorder caused by excessive alcohol intake represents a
global health care burden. ALD encompasses a broad spectrum of hepatic injuries including …

Developmental origins of NAFLD: a womb with a clue

SR Wesolowski, KCE Kasmi, KR Jonscher… - Nature reviews …, 2017 - nature.com
Abstract Changes in the maternal environment leading to an altered intrauterine milieu can
result in subtle insults to the fetus, promoting increased lifetime disease risk and/or disease …

Pyrroloquinoline-quinone is more than an antioxidant: a vitamin-like accessory factor important in health and disease prevention

KR Jonscher, W Chowanadisai, RB Rucker - Biomolecules, 2021 - mdpi.com
Pyrroloquinoline quinone (PQQ) is associated with biological processes such as
mitochondriogenesis, reproduction, growth, and aging. In addition, PQQ attenuates clinically …

Synthetic biology and engineered live biotherapeutics: toward increasing system complexity

T Ozdemir, AJH Fedorec, T Danino, CP Barnes - Cell systems, 2018 - cell.com
Recent advances in synthetic biology and biological system engineering have allowed the
design and construction of engineered live biotherapeutics targeting a range of human …

Critical roles of Kupffer cells in the pathogenesis of alcoholic liver disease: from basic science to clinical trials

T Zeng, CL Zhang, M Xiao, R Yang, KQ Xie - Frontiers in immunology, 2016 - frontiersin.org
Alcoholic liver disease (ALD) encompasses a spectrum of liver injury ranging from steatosis
to steatohepatitis, fibrosis, and finally cirrhosis. Accumulating evidences have demonstrated …

The injury and therapy of reactive oxygen species in intracerebral hemorrhage looking at mitochondria

J Qu, W Chen, R Hu, H Feng - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Intracerebral hemorrhage is an emerging major health problem often resulting in death or
disability. Reactive oxygen species (ROS) have been identified as one of the major …

Blood reflects tissue oxidative stress: a systematic review

NV Margaritelis, AS Veskoukis, V Paschalis… - Biomarkers, 2015 - Taylor & Francis
We examined whether the levels of oxidative stress biomarkers measured in blood reflect
the tissue redox status. Data from studies that measured redox biomarkers in blood, heart …

[HTML][HTML] Dietary effects of Bacillus subtilis fmbj on growth performance, small intestinal morphology, and its antioxidant capacity of broilers

K Bai, C Feng, L Jiang, L Zhang, J Zhang, L Zhang… - Poultry science, 2018 - Elsevier
This paper aimed to study the dietary effects of Bacillus subtilis fmbj (BS fmbj) on growth
performance, small intestinal histomorphology, and its antioxidant capacity of broilers at 21 d …

Precision medicine in alcoholic and nonalcoholic fatty liver disease via modulating the gut microbiota

S Bluemel, B Williams, R Knight… - American Journal of …, 2016 - journals.physiology.org
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) represent a
major health burden in industrialized countries. Although alcohol abuse and nutrition play a …