[HTML][HTML] Pathogenesis of diabetic complications: Exploring hypoxic niche formation and HIF-1α activation

J Bi, W Zhou, Z Tang - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Hypoxia is a common feature of diabetic tissues, which highly correlates to the progression
of diabetes. The formation of hypoxic context is induced by disrupted oxygen homeostasis …

Supplemental dietary curcumin improves testicular hemodynamics, testosterone levels, and semen quality in Baladi bucks in the non-breeding season

HR El-Sherbiny, M Fathi, H Samir, EA Abdelnaby - Theriogenology, 2022 - Elsevier
Improving the reproductive performance outside the breeding season could have a great
impact on the animals' breeding industry. Curcumin (CUR) is a polyphenol known for its …

Ameliorative effect of hesperidin on streptozotocin‐diabetes mellitus‐induced testicular DNA damage and sperm quality degradation in Sprague–Dawley rats

EH Aksu, FM Kandemir… - Journal of food …, 2021 - Wiley Online Library
This study aimed to investigate the effect of hesperidin on reproductive damage caused by
diabetes mellitus. A total of 24 adult male rats were divided into four groups: control group …

The formulation of curcumin: 2-hydroxypropyl-β-cyclodextrin complex with smart hydrogel for prolonged release of curcumin

L Nikolić, M Urošević, V Nikolić, I Gajić, A Dinić… - Pharmaceutics, 2023 - mdpi.com
Curcumin comes from the plant species Curcuma longa and shows numerous
pharmacological activities. There are numerous curcumin formulations with gels or …

Ameliorative Effects of Curcumin on Type 2 Diabetes Mellitus

Y Gu, Q Niu, Q Zhang, Y Zhao - Molecules, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM), a multifactorial and complicated metabolic disorder, is a
growing public health problem. Numerous studies have indicated that bioactive compounds …

Evaluation of lipidomic change in goat sperm after cryopreservation

B Xu, R Wang, Z Wang, H Liu, Z Wang… - Frontiers in veterinary …, 2022 - frontiersin.org
The current study aimed to detect the relationship between the spermatozoa cryotolerance
and the post-thawed sperm lipidome. Ejaculates from 20 goats, and performed a uniform …

Antioxidant and anti-inflammatory activity of curcumin transdermal gel in an IL-10 knockout mouse model of inflammatory bowel disease

FO Araujo, MB Felício, CF Lima, MS Piccolo… - Anais da Academia …, 2022 - SciELO Brasil
Inflammatory bowel diseases are a group of inflammatory disorders of the gastrointestinal
tract. Their prevalence is still low in Brazil, but the incidence is increasing annually. A variety …

Ameliorating effects of curcumin-loaded superparamagnetic iron oxide nanoparticles (SPIONs) on the mouse testis exposed to the transient hyperthermia: A molecular …

A Khosravi, A Hasani, K Rahimi, A Aliaghaei, M Pirani… - Acta …, 2020 - Elsevier
Background Testicular hyperthermia can have negative effects on male fertility. Despite
reported therapeutic benefits of curcumin, several factors often limit its application such as …

A comparative study between curcumin and curcumin nanoemulsion on high-fat, high-fructose diet-induced impaired spermatogenesis in rats

M Nasr, H Abd-Allah, OAH Ahmed-Farid… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives Curcumin is a promising nutraceutical with reported diverse therapeutic
properties, but of limited oral bioavailability. The current manuscript investigates the role of …

Curcumin displays a potent caloric restriction mimetic effect in an accelerated senescent model of rat

A Singh, P Srivastava, AK Verma, JK Arya, SI Rizvi - Biologia Futura, 2023 - Springer
Curcumin, a strong natural compound with numerous health benefits, is extracted from the
Curcuma longa. According to recent research findings, it also acts as a calorie restriction …