Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …

Inflammasomes are supramolecular platforms that organize in response to various damage-
associated molecular patterns and pathogen-associated molecular patterns. Upon …

Background The effectual immune response is crucial to defeat viral infections. However,
exuberant immune response with features of macrophage activation syndrome (MAS) lead …

The identification of patients with coronavirus disease 2019 and high risk of severe disease
is a challenge in routine care. We performed cell phenotypic, serum, and RNA sequencing …

Interleukin-1 is a cytokine with potent inflammatory and immune-amplifying effects, mainly
produced by macrophages during defensive reactions. In mammals, IL-1 is a superfamily of …

Summary The interleukin (IL)‐1 family of cytokines is a central regulator of a myriad of
immunological responses. It comprises several cytokines, including those belonging to the …

Abstract The interleukin-1 (IL-1) family of cytokines and receptors are implicated in the
functioning of innate and adaptive immunity and the genesis of inflammation. They are …

Autoimmune diseases (ADs) are a broad range of disorders which are characterized by long-
term inflammation and tissue damage arising from an immune response against one's own …

Chronic inflammation is frequently associated with myeloproliferative neoplasms (MPN), but
the role of inflammation in the pathogenesis of MPN remains unclear. Expression of the …

Abstract Background Coronavirus disease 19 (COVID-19) may have a severe course in
children. Multisystem inflammatory syndrome in children (MIS-C) is the post-COVID …