Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis

X He, X Fan, B Bai, N Lu, S Zhang, L Zhang - Pharmacological Research, 2021 - Elsevier
Pyroptosis is a form of programmed cell death activated by various stimuli and is
characterized by inflammasome assembly, membrane pore formation, and the secretion of …

Recent Progress in in vitro Models for Atherosclerosis Studies

J Chen, X Zhang, R Millican, T Lynd… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to
cardiovascular disease accounting for the high mortality in the United States. For developing …

Functions and therapeutic interventions of non-coding RNAs associated with TLR signaling pathway in atherosclerosis

R Margiana, F Alsaikhan, GRL Al-Awsi, I Patra… - Cellular …, 2022 - Elsevier
Nowadays, emerging data demonstrate that the toll-like receptor (TLR) signaling pathway
plays an important role in the progression of inflammatory atherosclerosis. Indeed …

Tetrazine-Based Ratiometric Nitric Oxide Sensor Identifies Endogenous Nitric Oxide in Atherosclerosis Plaques by Riding Macrophages as a Smart Vehicle

L Zhou, Z Wang, L Wang, X Zhang… - Journal of the American …, 2023 - ACS Publications
Atherosclerosis (AS) is the formation of plaques in blood vessels, which leads to serious
cardiovascular diseases. Current research has disclosed that the formation of AS plaques is …

[HTML][HTML] Recent advances in diverse nanosystems for nitric oxide delivery in cancer therapy

D Gao, S Asghar, R Hu, S Chen, R Niu, J Liu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Gas therapy has been proven to be a promising and advantageous treatment option for
cancers. Studies have shown that nitric oxide (NO) is one of the smallest structurally …

Metabolic syndrome in an aging society–role of oxidant-antioxidant imbalance and inflammation markers in disentangling atherosclerosis

S Dziegielewska-Gesiak - Clinical interventions in aging, 2021 - Taylor & Francis
Introduction The prevalence of metabolic syndrome among the elderly population is
growing. The elements of metabolic syndrome in an aging society are currently being …

Influence and implications of the molecular paradigm of nitric oxide underlying inflammatory reactions of the gastrointestinal tract of dog: a major hallmark of …

T Rana - Inflammatory Bowel Diseases, 2022 - academic.oup.com
Nitric oxide (NO), a pleiotropic free radical messenger molecule, is responsible for the
various cellular function of the gastrointestinal mucosa. It plays a major role in the …

[HTML][HTML] Taxifolin attenuates inflammation via suppressing MAPK signal pathway in vitro and in silico analysis

X Zhang, X Lian, H Li, W Zhao, X Li, F Zhou… - Chinese herbal …, 2022 - Elsevier
Objective Taxifolin is a natural flavonoid compound that can be isolated from onions, grapes,
oranges and grapefruit. It also acts as a medicine food homology with extraordinary …

Xiongshao Zhitong Recipe Attenuates Nitroglycerin-Induced Migraine-Like Behaviors via the Inhibition of Inflammation Mediated by Nitric Oxide Synthase

S Yang, C Chen, X Liu, Q Kang, Q Ma, P Li… - Frontiers in …, 2022 - frontiersin.org
Migraine is a major cause of disability worldwide, particularly in young adults and middle-
aged women. Xiongshao Zhitong Recipe (XZR) is a traditional Chinese medicine …

PKCδ regulates the vascular biology in diabetic atherosclerosis

P Qin, C He, P Ye, Q Li, C Cai, Y Li - Cell Communication and Signaling, 2023 - Springer
Diabetes mellitus, known for its complications, especially vascular complications, is
becoming a globally serious social problem. Atherosclerosis has been recognized as a …