Burn-induced coagulopathies: a comprehensive review

RL Ball, JW Keyloun, K Brummel-Ziedins, T Orfeo… - Shock, 2020 - journals.lww.com
Burn-induced coagulopathy is not well understood, and consensus on diagnosis,
prevention, and treatments are lacking. In this review, literature on burn-induced (and …

Pathophysiology of trauma-induced coagulopathy: disseminated intravascular coagulation with the fibrinolytic phenotype

M Hayakawa - Journal of intensive care, 2017 - Springer
In severe trauma patients, coagulopathy is frequently observed in the acute phase of trauma.
Trauma-induced coagulopathy is coagulopathy caused by the trauma itself. The …

D-dimer levels on admission and all-cause mortality risk in COVID-19 patients: a meta-analysis

DM Simadibrata, AM Lubis - Epidemiology & Infection, 2020 - cambridge.org
D-dimer level on admission is a promising biomarker to predict mortality in patients with
COVID-19. In this study, we reviewed the association between on-admission D-dimer levels …

The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of …

M Hayakawa, T Tagami, D Kudo, K Ono, M Aoki… - Journal of Intensive …, 2023 - Springer
Background The efficacies of fresh frozen plasma and coagulation factor transfusion have
been widely evaluated in trauma-induced coagulopathy management during the acute post …

Homocysteine as a marker for predicting disease severity in patients with COVID-19

A Keskin, GU Ustun, R Aci, U Duran - Biomarkers in Medicine, 2022 - Taylor & Francis
Aim: Our study was designed on the hypothesis that homocysteine levels are a prognostic
parameter that can predict the severity of COVID-19 disease. Materials & methods: 117 …

Cryoprecipitate attenuates the endotheliopathy of trauma in mice subjected to hemorrhagic shock and trauma

M Barry, A Trivedi, BY Miyazawa… - Journal of Trauma …, 2021 - journals.lww.com
BACKGROUND Plasma has been shown to mitigate the endotheliopathy of trauma.
Protection of the endothelium may be due in part to fibrinogen and other plasma-derived …

The impact of prehospital tranexamic acid on blood coagulation in trauma patients

P Stein, JD Studt, R Albrecht, S Müller… - Anesthesia & …, 2018 - journals.lww.com
BACKGROUND: There is limited data on prehospital administration of tranexamic acid (TXA)
in civilian trauma. The aim of this study was to evaluate changes in coagulation after severe …

Traumatized triad of complementopathy, endotheliopathy, and coagulopathy˗ Impact on clinical outcomes in severe polytrauma patients

Z Yang, TD Le, MO Simovic, B Liu, TL Fraker… - Frontiers in …, 2022 - frontiersin.org
Complementopathy, endotheliopathy, and coagulopathy following a traumatic injury are key
pathophysiological mechanisms potentially associated with multiple-organ failure (MOF) …

D-dimer predicts bleeding complication in out-of-hospital cardiac arrest resuscitated with ECMO

T Otani, H Sawano, T Natsukawa, R Matsuoka… - The American Journal of …, 2018 - Elsevier
Purpose In out-of-hospital cardiac arrest (OHCA) patients resuscitated with veno-arterial
extracorporeal membrane oxygenation (VA-ECMO), known as extracorporeal …

Early administration of fibrinogen concentrate is associated with improved survival among severe trauma patients: a single-centre propensity score-matched analysis

Y Itagaki, M Hayakawa, K Maekawa, T Saito… - World Journal of …, 2020 - Springer
Background Fibrinogen plays an important role in haemostasis during the early phase of
trauma, and low fibrinogen levels after severe trauma are associated with haemostatic …