Engineering bacteriophages for enhanced host range and efficacy: Insights from bacteriophage-bacteria interactions

HJ Jia, PP Jia, S Yin, LK Bu, G Yang… - Frontiers in Microbiology, 2023 - frontiersin.org
Bacteriophages, the most abundant organisms on earth, have the potential to address the
rise of multidrug-resistant bacteria resulting from the overuse of antibiotics. However, their …

Phage-encoded depolymerases as a strategy for combating multidrug-resistant Acinetobacter baumannii

MM Islam, NU Mahbub, WS Shin… - Frontiers in Cellular and …, 2024 - frontiersin.org
Acinetobacter baumannii, a predominant nosocomial pathogen, represents a grave threat to
public health due to its multiple antimicrobial resistance. Managing patients afflicted with …

An electrochemical biosensor based on phage-encoded protein RBP 41 for rapid and sensitive detection of Salmonella

Y Ding, Y Zhang, C Huang, J Wang, H Li, X Wang - Talanta, 2024 - Elsevier
Salmonellosis caused by Salmonella contaminated food poses a serious threat to human
health. The rapid and accurate detection of Salmonella is critical for preventing foodborne …

Using AlphaFold predictions in viral research

D Gutnik, P Evseev, K Miroshnikov… - Current Issues in …, 2023 - mdpi.com
Elucidation of the tertiary structure of proteins is an important task for biological and medical
studies. AlphaFold, a modern deep-learning algorithm, enables the prediction of protein …

Biological control of the fire blight pathogen Erwinia amylovora using bacteriophages

S Gayder, S Kammerecker, L Fieseler - Journal of Plant Pathology, 2024 - Springer
Bacteriophages offer unique benefits for the specific control of Erwinia amylovora, the
causative agent of fire blight in pome fruit. Unfortunately, the majority of described phages …

Review of AlphaFold 3: transformative advances in drug design and therapeutics

D Desai, SV Kantliwala, J Vybhavi, R Ravi, H Patel… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Google DeepMind Technologies Limited (London, United Kingdom) recently released its
new version of the biomolecular structure predictor artificial intelligence (AI) model named …

Prediction of Klebsiella phage-host specificity at the strain level

D Boeckaerts, M Stock, C Ferriol-González… - Nature …, 2024 - nature.com
Phages are increasingly considered promising alternatives to target drug-resistant bacterial
pathogens. However, their often-narrow host range can make it challenging to find matching …

[HTML][HTML] Biological characterization of Pseudomonas fluorescens phage Pf17397_F_PD1 and its application in food preservation

N Yan, H Xia, W Hou, H Wang, H Wang… - Journal of Food Protection, 2023 - Elsevier
In order to explore the application prospects of phages for controlling bacterial
contamination, a lytic phage Pf17397_F_PD1 (Later abbreviated as PD1) was isolated from …

New Obolenskvirus Phages Brutus and Scipio: Biology, Evolution, and Phage-Host Interaction

PV Evseev, MM Shneider, LV Kolupaeva… - International Journal of …, 2024 - mdpi.com
Two novel virulent phages of the genus Obolenskvirus infecting Acinetobacter baumannii, a
significant nosocomial pathogen, have been isolated and studied. Phages Brutus and Scipio …

Campycins are novel broad-spectrum antibacterials killing Campylobacter jejuni

A Zampara, YE Gencay, L Brøndsted… - Applied Microbiology …, 2024 - Springer
Pyocins are high molecular weight bacteriocins produced by Pseudomonas aeruginosa that
can be retargeted to new bacterial species by exchanging the pyocin tail fibers with …