Alkaloids and colon cancer: molecular mechanisms and therapeutic implications for cell cycle arrest

H Khan, W Alam, KF Alsharif, M Aschner, S Pervez… - Molecules, 2022 - mdpi.com
Cancer is the second most fatal disease worldwide, with colon cancer being the third most
prevalent and fatal form of cancer in several Western countries. The risk of acquisition of …

Plant peptides–redefining an area of ribosomally synthesized and post-translationally modified peptides

JR Chekan, LS Mydy, MA Pasquale… - Natural Product …, 2024 - pubs.rsc.org
Covering 1965 to February 2024Plants are prolific peptide chemists and are known to make
thousands of different peptidic molecules. These peptides vary dramatically in their size …

Ethnomedicinal uses of edible wild fruits (EWFs) in Swat Valley, Northern Pakistan

MPZ Khan, M Ahmad, M Zafar, S Sultana, MI Ali… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance This study documents the ethno-pharmacological
importance of Edible Wild Fruits (EWFs) resource in the wild floral emporium of Swat, Khyber …

Pomegranate seed oil nanoemulsions improve the photostability and in vivo antinociceptive effect of a non-steroidal anti-inflammatory drug

LM Ferreira, MHM Sari, VF Cervi, M Gehrcke… - Colloids and Surfaces B …, 2016 - Elsevier
The combination of pomegranate seed oil and ketoprofen in nanoemulsions aiming to
improve the antinociceptive effect was evaluated according to the writhing test and …

Antifungal potential of alkaloids as an emerging therapeutic target

H Khan, M S. Mubarak, S Amin - Current drug targets, 2017 - benthamdirect.com
Background: Fungal infections have been causing serious problems in all age groups,
especially in immune-compromised individuals. Various synthetic agents are in clinical …

Scientific investigation of crude alkaloids from medicinal plants for the management of pain

M Shoaib, SWA Shah, N Ali, I Shah, S Ullah… - … and Alternative Medicine, 2016 - Springer
Background Tissue damage is associated with pain, which is an alarming sign. Aspirin and
morphine have been widely used in recent decades for management of pain. Medicinal …

Phytochemicals intended for anticancer effects at preclinical levels to clinical practice: Assessment of formulations at nanoscale for non-small cell lung cancer (NSCLC …

THP Nguyen, VB Kumar, VK Ponnusamy, TTT Mai… - Process …, 2021 - Elsevier
Over the past few decades, many of the phytochemicals have been shown to possess
extraordinary anticancer effects, clinical tested, approved as drugs, and currently in use. A …

Ziziphus Oxyphylla hydro-methanolic extract ameliorates hypertension in L-NAME induced hypertensive rats through NO/cGMP pathway and suppression of oxidative …

B Shaukat, MH Mehmood, S Shah, H Anwar - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Ziziphus Oxyphylla belongs to family Ziziphus
and has been used traditionally in hypertension. It is enriched with quercetin and kaempferol …

In vivo antinociceptive and anti-inflammatory activities of umbelliferone isolated from Potentilla evestita

A Rauf, R Khan, H Khan, S Pervez… - Natural product …, 2014 - Taylor & Francis
This study was designed to evaluate the antinociceptive and anti-inflammatory activities of a
compound, umbelliferone, isolated from the chloroform fraction of Potentilla evestita in …

Mining raw plant transcriptomic data for new cyclopeptide alkaloids

D Kriger, MA Pasquale, BG Ampolini… - Beilstein Journal of …, 2024 - beilstein-journals.org
In recent years, genome and transcriptome mining have dramatically expanded the rate of
discovering diverse natural products from bacteria and fungi. In plants, this approach is often …