Overexpression of ATP-binding cassette (ABC) transporters is a cause of drug resistance in
a plethora of tumors. More recent evidence indicates additional contribution of these …

Long noncoding RNAs (lncRNAs) constitute large portions of the mammalian transcriptome
which appeared as a fundamental player, regulating various cellular mechanisms. LncRNAs …

Chemotherapy is one of the most important treatments for cancer therapy. However,
chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy …

Chemotherapy is currently one of the most effective methods in clinical cancer treatment.
However, chemotherapy resistance is an important reason for poor chemotherapy efficacy …

Background RNA profiling technologies at single-cell resolutions, including single-cell and
single-nuclei RNA sequencing (scRNA-seq and snRNA-seq, scnRNA-seq for short), can …

Intracerebral hemorrhage (ICH) is one of the most common refractory diseases. Long non-
coding RNAs (lncRNAs) play crucial roles in ICH. This study was designed to investigate the …

Early-stage detection of leukemia is a critical determinant for successful treatment of the
disease and can increase the survival rate of leukemia patients. The factors limiting the …

Background. Endometrial cancer (EC) is one of the most common gynaecological tumours in
the worldwide. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 …

Leukemia is a common malignant cancer of the hematopoietic system, whose pathogenesis
has not been fully elucidated. Long noncoding RNAs (lncRNAs) are transcripts longer than …

Cancer is a multifaceted disease that involves several molecular mechanisms including
changes in gene expression. Two important processes altered in cancer that lead to …