The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …

[HTML][HTML] Imprinting of the immune system by the microbiota early in life

Z Al Nabhani, G Eberl - Mucosal immunology, 2020 - Elsevier
The ontogeny and maturation of the immune system is modulated by the microbiota. During
fetal life, the mother's microbiota produces compounds that are transferred to the fetus and …

Gut microbiota resilience: definition, link to health and strategies for intervention

SK Dogra, J Doré, S Damak - Frontiers in microbiology, 2020 - frontiersin.org
The gut microbiota is a new frontier in health and disease. Not only many diseases are
associated with perturbed microbiota, but an increasing number of studies point to a cause …

The emerging role of the small intestinal microbiota in human health and disease

RAAA Ruigrok, RK Weersma, A Vich Vila - Gut microbes, 2023 - Taylor & Francis
The human gut microbiota continues to demonstrate its importance in human health and
disease, largely owing to the countless number of studies investigating the fecal microbiota …

Investigating causality with fecal microbiota transplantation in rodents: applications, recommendations and pitfalls

CE Gheorghe, NL Ritz, JA Martin, HR Wardill… - Gut …, 2021 - Taylor & Francis
In recent years, studies investigating the role of the gut microbiota in health and diseases
have increased enormously–making it essential to deepen and question the research …

'Layered immunity'and the 'neonatal window of opportunity'–timed succession of non‐redundant phases to establish mucosal host–microbial homeostasis after birth

MW Hornef, N Torow - Immunology, 2020 - Wiley Online Library
The intricate host–microbial interaction and the overwhelming complexity of the mucosal
immune system in the adult host raise the question of how this system is initially established …

NOD2 deficiency increases retrograde transport of secretory IgA complexes in Crohn's disease

N Rochereau, X Roblin, E Michaud, R Gayet… - Nature …, 2021 - nature.com
Intestinal microfold cells are the primary pathway for translocation of secretory IgA (SIgA)-
pathogen complexes to gut-associated lymphoid tissue. Uptake of SIgA/commensals …

[HTML][HTML] Gut microbiota and inflammatory bowel disease: The current status and perspectives

L Zheng, XL Wen - World journal of clinical cases, 2021 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease that affects the
gastrointestinal tract. It is argued that environment, microbiome, and immune-mediated …

Gut Dysbiosis and Clostridioides difficile Infection in Neonates and Adults

IM Vasilescu, MC Chifiriuc, GG Pircalabioru… - Frontiers in …, 2022 - frontiersin.org
In this review, we focus on gut microbiota profiles in infants and adults colonized (CDC) or
infected (CDI) with Clostridioides difficile. After a short update on CDI epidemiology and …

High red meat intake exacerbates dextran sulfate-induced colitis by altering gut microbiota in mice

D Li, M Cui, F Tan, X Liu, P Yao - Frontiers in nutrition, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a serious hazard to public health, but the precise
etiology of the disease is unclear. High intake of red meat diet is closely related to the …