The functional diversity of natural killer (NK) cell repertoires stems from differentiation,
homeostatic, receptor–ligand interactions and adaptive-like responses to viral infections. In …

T helper (Th) 17 and regulatory T (Treg) cells are highly plastic CD4+ Th cell subsets, being
able not only to actively adapt to their microenvironment, but also to interconvert, acquiring …

Glioblastoma (GBM) is an aggressive brain cancer with limited therapeutic options. Natural
killer (NK) cells are innate immune cells with strong anti-tumor activity and may offer a …

Histone methyltransferases (HMTs) are crucial in gene regulation and function, yet their role
in natural killer (NK) cell biology within the tumor microenvironment (TME) remains largely …

Despite therapeutic advancements, multiple myeloma (MM) remains incurable. NK cells
have emerged as a promising option for the treatment of MM. NK cells are heterogenous …

Low fracture toughness, low-temperature degradation (LTD) susceptibility, and inadequate
soft tissue integration greatly limit the application of zirconia ceramic abutment. Integrating …

Background High levels of the polyunsaturated fatty acid arachidonic acid (AA) within the
ovarian carcinoma (OC) microenvironment correlate with reduced relapse-free survival …

Glioblastoma is the most common brain cancer, with a 5-year survival rate of less than 10%.
This grim prognosis highlights the urgent need for novel therapeutic approaches. In this …

Transcription factor partners can cooperatively bind to DNA composite elements to augment
gene transcription. Here, we report a novel protein-DNA binding screening pipeline, termed …

Adipose tissue physiology and homeostasis depends on a healthy vascular network.
Vascular malfunction is a hallmark of obesity, and vascular endothelial dysfunction, in …