[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential

YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …

Polyphenols in cancer prevention: New insights

G Briguglio, C Costa, M Pollicino… - International …, 2020 - spandidos-publications.com
A huge volume of literature data suggests that a diet rich in fruits and vegetables, mostly due
to the contribution of natural polyphenols, could reduce the incidence of specific cancers …

[HTML][HTML] Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis

R Zhang, T Pan, Y Xiang, M Zhang, H Xie, Z Liang… - Bioactive materials, 2022 - Elsevier
Curcumenol, an effective ingredient of Wenyujin, has been reported that exerted its
antitumor potential in a few cancer types. However, the effect and molecular mechanism of …

Curcumin-based nanoformulations: A promising adjuvant towards cancer treatment

S Hafez Ghoran, A Calcaterra, M Abbasi, F Taktaz… - Molecules, 2022 - mdpi.com
Throughout the United States, cancer remains the second leading cause of death.
Traditional treatments induce significant medical toxic effects and unpleasant adverse …

Traditional Chinese Medicine has great potential as candidate drugs for lung cancer: A review

Z Wei, J Chen, F Zuo, J Guo, X Sun, D Liu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance With high mortality and morbidity rates, lung cancer (LC)
has become one of the major threats to human health. The treatment strategies for LC …

Targeting Bcl-2 for cancer therapy

L Zhang, Z Lu, X Zhao - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Apoptosis deficiency is one of the most important features observed in neoplastic diseases.
The Bcl-2 family is composed of a subset of proteins that act as decisive apoptosis …

Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022 - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

Polymeric nanomicelles of curcumin: Potential applications in cancer

L Farhoudi, P Kesharwani, M Majeed… - International Journal of …, 2022 - Elsevier
Natural compounds, primarily derived from plants, have been isolated and evaluated as
alternative and complementary treatments for cancer. Curcumin has been proven to be …

Natural products and their derivatives as immune check point inhibitors: Targeting cytokine/chemokine signalling in cancer

M Gupta, K Chandan, M Sarwat - Seminars in cancer biology, 2022 - Elsevier
Cancer immunotherapy is the new generation and widely accepted form of tumour
treatment. It is, however, associated with exclusive challenges which include organ-specific …

Curcumin and melphalan cotreatment induces cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells

CLA Passos, RM Polinati, C Ferreira… - Scientific Reports, 2023 - nature.com
Breast cancer is the second most common type of cancer worldwide and the leading cause
of cancer death in women. Dietary bioactive compounds may act at different stages of …