Regulated forms of cell death in fungi

AP Gonçalves, J Heller, A Daskalov, A Videira… - Frontiers in …, 2017 - frontiersin.org
Cell death occurs in all domains of life. While some cells die in an uncontrolled way due to
exposure to external cues, other cells die in a regulated manner as part of a genetically …

Calcium transport proteins in fungi: the phylogenetic diversity of their relevance for growth, virulence, and stress resistance

M Lange, E Peiter - Frontiers in microbiology, 2020 - frontiersin.org
The key players of calcium (Ca2+) homeostasis and Ca2+ signal generation, which are
Ca2+ channels, Ca2+/H+ antiporters, and Ca2+-ATPases, are present in all fungi. Their …

Translation inhibition by rocaglates activates a species-specific cell death program in the emerging fungal pathogen Candida auris

KR Iyer, L Whitesell, JA Porco Jr, T Henkel, LE Brown… - MBio, 2020 - Am Soc Microbiol
Fungal infections are a major contributor to infectious disease-related deaths worldwide.
Recently, global emergence of the fungal pathogen Candida auris has caused considerable …

Ca2+ permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death

M Salgado, V Márquez-Miranda… - Proceedings of the …, 2024 - National Acad Sciences
Pannexin1 hemichannels (Panx1 HCs) are found in the membrane of most mammalian cells
and communicate the intracellular and extracellular spaces, enabling the passive transfer of …

Fungal cell death: the beginning of the end

AM Rico-Ramírez, AP Gonçalves, NL Glass - Fungal Genetics and Biology, 2022 - Elsevier
Death is an important part of an organism's existence and also marks the end of life. On a
cellular level, death involves the execution of complex processes, which can be classified …

Hypotonic stress-induced calcium signaling in Saccharomyces cerevisiae involves TRP-like transporters on the endoplasmic reticulum membrane

M Rigamonti, S Groppi, F Belotti, R Ambrosini, G Filippi… - Cell calcium, 2015 - Elsevier
Saccharomyces cerevisiae cells respond to hypotonic stress (HTS) by a cytosolic calcium
rise, either generated by an influx of calcium from extracellular medium, when calcium is …

Calcium homeostasis and signaling in fungi and their relevance for pathogenicity of yeasts and filamentous fungi

R Tisi, M Rigamonti, S Groppi, F Belotti - AIMS Molecular Science, 2016 - boa.unimib.it
Though fungi show peculiarities in the purposes and specific traits of calcium signaling
pathways, the general scheme and the most important players are well conserved if …

Ca2+ Signalling Differentially Regulates Germ-Tube Formation and Cell Fusion in Fusarium oxysporum

SM Kurian, A Lichius, ND Read - Journal of Fungi, 2022 - mdpi.com
Fusarium oxysporum is an important plant pathogen and an emerging opportunistic human
pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes …

Aureoverticillactam, a Potent Antifungal Macrocyclic Lactam from Streptomyces aureoverticillatus HN6, Generates Calcium Dyshomeostasis-Induced Cell Apoptosis via the Phospholipase …

LY Wang, YF Zhang, DY Yang, SJ Zhang… - …, 2021 - Am Phytopath Society
Extensive efforts have been made to discover new biofungicides of high efficiency for control
of Fusarium oxysporum f. sp. cubense race 4, a catastrophic soilborne phytopathogen …

Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus

A Munoz, M Bertuzzi, J Bettgenhaeuser… - PLoS …, 2015 - journals.plos.org
Aspergillus fumigatus is an inhaled fungal pathogen of human lungs, the developmental
growth of which is reliant upon Ca2+-mediated signalling. Ca2+ signalling has regulatory …