Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European …

J Tunon, L Badimon, ML Bochaton-Piallat… - Cardiovascular …, 2019 - academic.oup.com
Dysregulated lipid metabolism induces an inflammatory and immune response leading to
atherosclerosis. Conversely, inflammation may alter lipid metabolism. Recent treatment …

Lactiplantibacillus plantarum strains KABP011, KABP012, and KABP013 modulate bile acids and cholesterol metabolism in humans

T Padro, V Santisteban, P Huedo… - Cardiovascular …, 2024 - academic.oup.com
Aims Probiotics with high bile salt hydrolase (BSH) activity have shown to promote
cardiovascular health. However, their mechanism (s) of action remain poorly understood …

High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical …

S Ben-Aicha, R Escate, L Casaní, T Padró… - Cardiovascular …, 2020 - academic.oup.com
Abstract Aims High-density lipoproteins (HDLs) are circulating micelles that transport
proteins, lipids, and miRNAs. HDL-transported miRNAs (HDL-miRNAs) have lately received …

Pig and mouse models of hyperlipidemia and atherosclerosis

GS Getz, CA Reardon - Atherosclerosis: Methods and Protocols, 2022 - Springer
Atherosclerosis is a chronic inflammatory disorder that is the underlying cause of most
cardiovascular disease. Resident cells of the artery wall and cells of the immune system …

CETP inhibition and HDL: what is the trial REVEALing?

L Badimon - Cardiovascular Research, 2018 - academic.oup.com
The recently published Randomized EValuation of the Effects of Anacetrapib through Lipid-
modification (REVEAL/HPS3/TIMI55) trial 1 assessed in 30 449 patients aged 50 and older …